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ProteomicsCoupling tRNAGly gene redundancy with staphylococcal cell wall integrity, antibiotic susceptibility and virulence potential
Redundancy in the number of tRNA genes which occur across species is poorly understood and, in many cases, remains essentially unexplored. In Staphylococcus aureus, several tRNAGly genes encode isoacceptors that either participate in protein synthesis or cell wall formation, upon aminoacylation by t...
ORGANISM(S): Staphylococcus aureus 
2025-07-21 | PXD059048 | Pride
Genome editing Trna-mediated metabolism regulation Staphylococcus aureus Trna gene redundancy 
GenomicsCoupling tRNAGly gene redundancy with staphylococcal cell wall integrity, antibiotic susceptibility and virulence potential
Coupling tRNAGly gene redundancy with staphylococcal cell wall integrity, antibiotic susceptibility and virulence potential
PRJNA1204950 | ENA
UnknownThe layered costs and benefits of translational redundancy.
Not available
S-EPMC9981150 | biostudies-literature
UnknownCoupling tRNAGly gene redundancy with staphylococcal cell wall integrity, antibiotic susceptibility, and virulence potential.
Not available
S-EPMC12256121 | biostudies-literature
TranscriptomicsCoupling tRNAGly gene redundancy with staphylococcal cell wall integrity, antibiotic susceptibility and virulence potential
Redundancy in the number of tRNA genes which occur across species is poorly understood and, in many cases, remains essentially unexplored. In Staphylococcus aureus, several tRNAGly genes encode isoacceptors that either participate in protein synthesis or cell wall formation, upon aminoacylation by t...
ORGANISM(S): Staphylococcus aureus 
2025-07-16 | GSE285601 | GEO
UnknownA Comprehensive tRNA Genomic Survey Unravels the Evolutionary History of tRNA Arrays in Prokaryotes.
Not available
S-EPMC4758250 | biostudies-literature
TranscriptomicsThe anti-Shine-Dalgarno sequence drives translational pausing and codon choice in bacteria
Protein synthesis by ribosomes takes place on a linear substrate but at variable speeds. Transient pausing of ribosomes can impact a variety of co-translational processes, including protein targeting and folding. These pauses are influenced by the sequence of the mRNA. Thus redundancy in the genetic...
ORGANISM(S): Escherichia coli 
2012-04-01 | E-GEOD-35641 | biostudies-arrayexpress
TranscriptomicsHydro-tRNAseq of human cell lines HACAT and HepG2
To quantify tRNA expression, we perform hydro-tRNA sequencing (Gogakos et al. 2017) in HACAT (keratinoytes) and HepG2 (liver) human cell lines. This study contains 6 samples. Three replicates for each of the five cell lines. This data complements our previously published data (GEO: GSE137834), whic...
ORGANISM(S): Homo sapiens 
2021-03-15 | E-MTAB-9905 | biostudies-arrayexpress
UnknownCollaboration of tRNA modifications and elongation factor eEF1A in decoding and nonsense suppression.
Not available
S-EPMC6109124 | biostudies-literature
GenomicsTFIIIC regulates SMC complex binding and 3D DNA contacts between tRNA genes [ChIP-Seq]
Transcription factor IIIC (TFIIIC) is a multi-subunit protein complex that recruits RNA polymerase III (Pol III) to the majority of its target genes. Evolutionarily conserved overlap between TFIIIC binding sites and the structural maintenance of chromosomes (SMC) complexes suggested a role for TFIII...
ORGANISM(S): Caenorhabditis elegans 
2026-09-18 | GSE338224 | GEO
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