Sort   by:  
 Page size 
ProteomicsCharacterization of two mutually orthogonal pyrrolysyl-tRNA synthetase/tRNAPyl pairs residing in the same organism
Site-specific incorporation of distinct non-canonical amino acids (ncAAs) into proteins via genetic code expansion requires mutually orthogonal aminoacyl-tRNA synthetase (aaRS)/tRNA pairs. Pyrrolysyl–tRNA synthetase (PylRS)/tRNAPyl pairs are ideal for genetic code expansion and have been extensively...
ORGANISM(S): Haloferax volcanii (Halobacterium volcanii) 
2022-05-12 | PXD027053 | Pride
Mutually orthogonal Pyrrolysyl-trna synthetase Archaea Trnapyl Genetic code expansion 
UnknownqPCR assays to quantitate tRNApyl and pylRS expression in engineered cell lines.
Not available
S-EPMC6508675 | biostudies-literature
UnknownThe tRNA discriminator base defines the mutual orthogonality of two distinct pyrrolysyl-tRNA synthetase/tRNAPyl pairs in the same organism.
Not available
S-EPMC9071458 | biostudies-literature
GenomicsSaccharomyces cerevisiae
Quadruply orthogonal pyrrolysyl-tRNA synthetase/tRNAPyl pairs in yeast
PRJNA1330968 | ENA
UnknownRationally evolving tRNAPyl for efficient incorporation of noncanonical amino acids.
Not available
S-EPMC4678846 | biostudies-literature
UnknownUpdate of the Pyrrolysyl-tRNA Synthetase/tRNAPyl Pair and Derivatives for Genetic Code Expansion.
Not available
S-EPMC9945579 | biostudies-literature
UnknownLinker and N-Terminal Domain Engineering of Pyrrolysyl-tRNA Synthetase for Substrate Range Shifting and Activity Enhancement.
Not available
S-EPMC7156790 | biostudies-literature
UnknownQuintuply orthogonal pyrrolysyl-tRNA synthetase/tRNAPyl pairs.
Not available
S-EPMC7615293 | biostudies-literature
UnknownAncestral archaea expanded the genetic code with pyrrolysine.
Not available
S-EPMC9630628 | biostudies-literature
UnknownPyrrolysine Aminoacyl-tRNA Synthetase as a Tool for Expanding the Genetic Code.
Not available
S-EPMC11764691 | biostudies-literature
Sort   by:  
 Page size