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ProteomicsHuman cTnT fragmentation in serum
Cardiac troponin T (cTnT) is a highly cardiospecific protein commonly used in the diagnosis of acute myocardial infarction (AMI), but is subject to proteolytic degradation upon its release in the circulation. In this study, a targeted mass spectrometry assay was developed to detect peptides which ar...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080749 | MassIVE
TranscriptomicsTranscription profiling of zebrafish embryos following cardiac troponin T2 knockdown
We examined the transcriptional effect of preventing cardiac contraction in zebrafish embryos which can be deprived of circulation without experiencing hypoxia since the fish obtain sufficient oxygen via diffusion. Morpholino antisense knockdown of cardiac troponin T2 (tnnt2) prevented cardiac contr...
ORGANISM(S): Danio rerio 
2009-07-05 | E-GEOD-16740 | biostudies-arrayexpress
ProteomicsMass spectrometric ITEM-TWO analyses of interactions between human cardiac Troponin T (hcTnT) peptides and the M7 or the M11.7 antiTnT antibodies.
Molecular characterization of antibodies M7, and M11.7, as well as the antiTNF alpha antibody in addition to the synthetic peptides P11-P17 and P21-P32. The M7 and M11.7 anti-human cardiac Troponin T (antihcTnT) antibodies from Roche Diagnostics Deutschland GmbH (Mannheim, Germany) and the antiTNF a...
ORGANISM(S): Homo sapiens (Human) 
2025-05-20 | PXD058812 | Pride
Item-two Troponin t Offline nanoesi-ms 
ProteomicsTroponin T mutations associated with HCM
Proteomic comparison of heart muscle wild type and transgenic troponin T mice (R278C and 179N mutations).
ORGANISM(S): Mus Musculus 
2016-02-27 | MSV000079538 | MassIVE
TranscriptomicsTranscription profiling of wild type and delK210 cTnT knock-in mouse heart to study dilated cardiomyopathy
Changes in the gene expression in the heart of knock-in mouse model of dilated cardiomyopathy caused by delK210 mutation in cardiac troponin T.
ORGANISM(S): Mus musculus 
2008-09-04 | E-MEXP-1340 | biostudies-arrayexpress
TranscriptomicsmiR-487b, miR-3963 and miR-6412 delayed myogenic differentiation in C2C12 mouse myoblast-derived cells.
We newly identified skeletal muscle differentiation-associated miRNAs by comparing miRNA expression profile between C2C12 cell and Wnt4-overexpressing C2C12 cell. miR-487b, miR-3963 and miR-6412 are significantly down-regulated in differentiating C2C12 cells, and transfection of their mimics result...
ORGANISM(S): Mus musculus 
2015-11-24 | E-GEOD-63454 | biostudies-arrayexpress
GenomicsSmall RNA Sequencing in Polytrauma Patients: High vs. Low Troponin T Levels
Small RNA Sequencing in Polytrauma Patients: High vs. Low Troponin T Levels
PRJNA1209886 | ENA
ProteomicsAberrant troponin post-translational modifications with TNNT1 mutations
TNNT1 mutations are associated with congenital myopathies. Here, we aimed to investigate whether troponin T post-translational modifications would be affected by the mutations. For that, we used muscle biopsy specimens from patients with TNNT1 mutations and controls. We then defined the nature and l...
ORGANISM(S): Homo sapiens (Human) 
2025-01-08 | PXD054504 | Pride
Troponin Genetic disorder Skeletal muscle 
TranscriptomicsCardiac transcription factors in HL-1 cells: gene expression and genome binding profiling
[1] Gene expression profiling in Gata4, Mef2a knockdown in HL-1 cells. HL-1 cells infected with adenovirus expressing either control siRNA or Gata4, and Gata4 & Mef2a siRNA. [2] Genome-wide maps of cardiac transcription factors binding region in HL-1 cells. We performed bio-ChIP-seq using streptavi...
ORGANISM(S): Mus musculus 
2011-03-02 | E-GEOD-21529 | biostudies-arrayexpress
UnknownDifferences in Troponin I and Troponin T Release in High-Performance Athletes Outside of Competition.
Not available
S-EPMC10816948 | biostudies-literature
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