Trypanosome - OmicsDI

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Unknown (925)
Genomics (139)
Proteomics (85)
Transcriptomics (81)
Metabolomics (6)
Models (2)
Other (1)

Organisms

Schizosaccharomyces pombe (79)
Oryza sativa Indica Group (79)
Sinorhizobium meliloti BL225C (79)
Sus scrofa domesticus (79)
Ostreococcus tauri (79)
Saccharomyces cerevisiae (79)
Staphylococcus aureus (79)
Rattus norvegicus (79)
Escherichia coli (79)
Cyanophora paradoxa (79)
Trypanosoma brucei (43)
Trypanosoma brucei brucei (20)
Mus musculus (8)
Homo sapiens (7)
Bos taurus (5)
Trypanosoma evansi (3)
Sodalis glossinidius (2)
Bombus terrestris (2)
Trypanosoma congolense (2)
Trypanosoma theileri (1)
Trypanosoma vivax (1)
Leishmania major (1)
Trypanosoma brucei brucei TREU927 (1)
Bodo saltans (1)
Anopheles gambiae (1)
Glossina fuscipes fuscipes (1)
Glossina morsitans morsitans (1)
Glossina palpalis (1)
Trypanosoma equiperdum (1)
Bos indicus (1)

Organisms

Trypanosoma brucei (10)
Trypanosoma brucei brucei (9)
Glossina morsitans morsitans (3)
Glossina fuscipes fuscipes (3)
Mus musculus (3)
Rhodnius prolixus (2)
Musca domestica (2)
Homo sapiens (2)
Glossina palpalis (1)
Glossina palpalis palpalis (1)
Trypanosoma vivax (1)
Glossina pallidipes (1)
Trypanosoma evansi (1)
Trypanosoma congolense (1)
Spiroplasma endosymbiont of Glossina fuscipes fuscipes (1)
Bombus terrestris (1)
bee metagenome (1)
gut metagenome (1)

Repository

ENA (126)
pride (79)
biostudies-arrayexpress (61)
geo (32)
MetaboLights (6)
MassIVE (3)
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PAXDB (2)
ExpressionAtlas (1)
EGA (1)
iProX (1)

Tissue

Permanent cell line cell (11)
Cell culture (10)
Blood cell (2)
Spleen (1)
Liver (1)
Peritrophic membrane (1)
Procyclic form (1)
Bloodstream form (1)
Cell line cell culturing (1)
Midgut (1)
Diploid cell (1)
Blood serum (1)
Cell suspension culture (1)

Disease

Trypanosomiasis (25)
Sleeping sickness (1)

Technology Type

Mass Spectrometry (79)
Shotgun proteomics (41)
Affinity purification coupled with mass spectrometry proteomics (22)
Gel-based experiment (17)
Bottom-up proteomics (10)
Mass spectrometry (6)
Data-dependent acquisition (3)
Chemical cross-linking coupled with mass spectrometry proteomics (2)
SWATH MS (1)
Data-independent acquisition (1)

Instrument Platform

Illumina HiSeq 2000 (16)
NextSeq 550 (3)
NextSeq 500 (2)
Orbitrap Fusion Lumos (2)
Liquid Chromatography MS - Alternating (LC-MS (Alternating)) (2)
Chromium Controller (1)
Illumina Genome analyzer IIx (1)
ScanArray 4000XL [PerkinElmer] (1)
Illumina Genome Analyzer II (1)
NextSeq 2000 (1)
Illumina HiSeq 1000 (1)
MinION (1)
Illumina MiSeq (1)
Illumina HiSeq 2500 (1)
- (1)
TimsTOF HT (1)
QExactive (Thermo Scientific) (1)
Orbitrap Fusion (Thermo Fisher Scientific)_negative (1)
Orbitrap Fusion (Thermo Fisher Scientific) (1)
LTQ Orbitrap Classic (Thermo Scientific) (1)
Exactive (Thermo Scientific) (1)
Liquid Chromatography MS - alternating - hilic (1)
Waters: QtofI (1)
ThermoFinigan LTQ (1)

Publication Date

2022 (20)
2021 (18)
2017 (16)
2023 (16)
2024 (13)
2020 (13)
2018 (11)
2014 (11)
2025 (9)
2013 (9)
2010 (9)
2026 (9)
2008 (7)
2016 (6)
2015 (5)
2019 (4)
2009 (4)
2012 (2)
2011 (2)
2007 (2)
2006 (2)
2005 (1)

UNIPROT ID/AC

Q383W3_TRYB2 (2)
Q4GZ71_TRYB2 (2)
Q38DR4_TRYB2 (2)
Q386U1_TRYB2 (2)
Q38B56_TRYB2 (2)
Q57ZK0_TRYB2 (2)
Q38AT6_TRYB2 (2)
Q57XB8_TRYB2 (2)
Q382Q1_TRYB2 (2)
Q57TY7_TRYB2 (2)
Q385Y2_TRYB2 (2)
Q585Y7_TRYB2 (2)
Q388P9_TRYB2 (2)
Q582G3_TRYB2 (2)
Q388W0_TRYB2 (2)
Q57WW5_TRYB2 (2)
Q582Q6_TRYB2 (2)
Q581U7_TRYB2 (2)
Q38F96_TRYB2 (2)
Q38EX6_TRYB2 (2)
Q38BF0_TRYB2 (2)
Q38C15_TRYB2 (2)
Q38BP5_TRYB2 (2)
Q38BZ8_TRYB2 (2)
Q386D7_TRYB2 (2)
Q389L8_TRYB2 (2)
Q587G0_TRYB2 (2)
Q384S0_TRYB2 (2)
Q57WF9_TRYB2 (2)
Q57ZD7_TRYB2 (2)

CHEBI ID

CHEBI:15978 (5)
CHEBI:32816 (5)
CHEBI:17835 (4)
CHEBI:16027 (4)
CHEBI:30831 (4)
CHEBI:27596 (4)
CHEBI:17712 (4)
CHEBI:16857 (4)
CHEBI:16828 (4)
CHEBI:17115 (4)
CHEBI:16643 (4)
CHEBI:18050 (4)
CHEBI:16084 (2)
CHEBI:29052 (2)
CHEBI:28013 (2)
CHEBI:17754 (2)
CHEBI:17794 (2)
CHEBI:16001 (2)
CHEBI:15422 (2)
CHEBI:16761 (2)
CHEBI:16908 (2)
CHEBI:15846 (2)
CHEBI:16108 (2)
CHEBI:18021 (2)
CHEBI:4170 (1)
CHEBI:4167 (1)
CHEBI:35780 (1)
CHEBI:15361 (1)
CHEBI:17665 (1)
CHEBI:17234 (1)

Metabolite Name

Hypoxanthine (4)
Cis-Aconitate (4)
Taurine (4)
L-Arginine (4)
L-Phenylalanine (4)
L-Asparagine (4)
L-Glutamine (4)
L-Alanine (4)
L-Threonine (4)
L-Serine (4)
Xanthine (4)
2-Ethylhexyl phthalate (3)
N-Acetyl-L-histidine (3)
Sn-glycero-3-Phosphocholine (3)
Choline phosphate (3)
L-Cystathionine (3)
L-Citrulline (3)
L-Aspartate (3)
Orthophosphate (3)
Urocanate (3)
D-Gluconic acid (3)
2-Acetolactate (3)
Glycerophosphoglycerol (3)
5-Hydroxypentanoate (3)
Phosphonate (3)
Hydroxypyruvate (3)
Urate (3)
Mesaconate (3)
HEPES (3)
Phenolsulfonphthalein (3)

First Public Date

2022 (16)
2018 (15)
2026 (13)
2023 (12)
2021 (10)
2013 (10)
2025 (8)
2019 (8)
2017 (8)
2014 (8)
2020 (5)
2010 (4)
2024 (3)
2015 (3)
2016 (2)
2011 (1)

Modelling Approach

Ordinary differential equation model (2)

Lab affiliation

Department of Biochemistry and Functional Proteomics, Institute of Biology II, Faculty of Biology and BIOSS Centre for Biological Signalling Studies, University of Freiburg, 79104 Freiburg im Breisgau, Germany (6)
University of Edinburgh (4)
Faculty of Chemistry and Pharmacy, Biochemistry II, Theodor Boveri-Institute, University of Würzburg, Germany (2)
Biocenter, Faculty of Biology, Genetics Ludwig-Maximilians-University Munich (LMU) 82152 Martinsried, Germany (2)
Department of Chemistry and Biochemistry University of Bern Switzerland (2)
Zentrum für Molekulare Biologie (ZMBH), Mass Spectrometry and Proteomics (2)
Institute of Molecular Genetics, Prague (2)
Institut Pasteur, Université Paris Cité, Trypanosome Molecular Biology, Department of Parasites and Insect Vectors, F-75015, Paris, France (1)
Division of Biological Chemistry & Drug Discovery University of Dundee (1)
Wellcome Centre for Cell Biology, The University of Edinburgh (1)
College of Science and Mathematics, Kennesaw State University, USA (1)
University Heidelberg, Centre for molecular biology, mass spectrometry and proteomics core facility (1)
University of Edinburgh Institute of Immunology and Infection Research (1)
Cirad Bios UMR Intertryp, Campus international de Baillarguet TA A 17/G F-34398 Montpellier Cedex 5 France (1)
Department of Pharmaceutical Sciences, University at Buffalo and NYS Center of Excellence in Bioinformatics and Life Sciences, University at Buffalo, USA (1)
MPI for Biochemistry (1)
University of Glasgow (1)
Head of Drug Discovery and Evaluation Center for Research of Pathogenicity and Virulence of Parasites Charles University in Prague, BIOCEV Průmyslová 595 252 50 Vestec Czech Republic (1)
Mark C. Field Professor of Cell Biology and Parasitology Division of Biological Chemistry & Drug Discovery School of Life Sciences University of Dundee Dundee United Kingdom (1)
The Wellcome Centre for Anti-Infectives Research School of Life Sciences University of Dundee Dow Street, Dundee DD1 5EH, Scotland, UK (1)
Biological Chemistry and Drug Discovery, School of Life Sciences, University od Dundee, Dundee (1)
Univ. Bordeaux, CNRS, MFP, UMR 5234, F-33000 Bordeaux, France (1)
Laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP), Université de Bordeaux, CNRS UMR-5234, Bordeaux, France (1)
Kennesaw State University (1)
Univeristy of Dundee (1)
Infection Biology (1)
Bar-Ilan University (1)
School of Life Sciences University of Nottingham Nottingham UK (1)
Biocenter, Faculty of Biology, Genetics Ludwig-Maximilians-University Munich (LMU) 82152 Martinsried, Germany (1)
Biomedical & Life Sciences, Lancaster University UK (1)

IsPrivate

False (2)

Classification

protozoa (22)

Modification

N6 (1)
Not available (1)

Study type

RNA-seq of coding RNA (22)
Transcription profiling by array (20)
Cell line - High-throughput sequencing (4)
DNA-seq (4)
Other (2)
RNA-seq of coding RNA from single cells (2)
Transcription profiling by SAGE (1)
High-throughput sequencing (1)
RNAi profiling by array (1)
RIP-seq (1)
RNA-seq of non coding RNA (1)

Release Date

2021 (79)
2022 (63)
2017 (60)
2015 (58)
2023 (58)
2019 (57)
2016 (57)
2013 (57)
2020 (55)
2014 (55)
2018 (51)
2010 (41)
2009 (41)
2024 (40)
2025 (39)
2012 (33)
2008 (30)
2011 (29)
2006 (22)
2007 (20)
2005 (8)
2002 (6)
2026 (5)
2001 (5)
2003 (4)
1999 (3)
1997 (3)
2004 (2)
2000 (2)
1998 (2)

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The roles of 3’-exoribonucleases and the exosome in trypanosome mRNA degradation

The roles of 3’-exoribonucleases and the exosome in trypanosome mRNA degradation; 30 min after actinomycin D +sinefungin, RNAi against CAf1, CNOT10, PAN2. These are really old data that hadn't been deposited.The datasets called RNA1, RNA2, RNA3 and RNA4 are almost certainly, from their location in t...

ORGANISM(S): Trypanosoma brucei brucei

2021-03-11 | E-MTAB-10260 | biostudies-arrayexpress

ALBA proteins are stage regulated during trypanosome development in the tsetse fly and participate in differentiation.

Not available

S-EPMC3216647 | biostudies-literature

High throughput decoding of anti trypanosomal drug efficacy and resistance

We used all five current human African trypanosomiasis drugs for genome-scale RNA interference (RNAi) target sequencing (RIT-seq) screens in Trypanosoma brucei, revealing the transporters, organelles, enzymes and metabolic pathways that function to facilitate anti-trypanosomal drug action. RIT-seq p...

ORGANISM(S): Trypanosoma brucei

2011-11-29 | E-ERAD-30 | biostudies-arrayexpress

Interactions of CAF1-NOT complex components from Trypanosoma brucei

Our trypanosome yeast two-hybrid prey library was made by random shotgun genomic cloning. NOT2, NOT10, NOT11 and CAF40 were used as baits to screen the library by mating. Diploid progeny were subjected to selection, resulting in between 100 and 800 surviving colonies, from which inserts were amplifi...

ORGANISM(S): Trypanosoma brucei

2022-01-14 | E-MTAB-4946 | biostudies-arrayexpress

Gluconeogenesis is essential for trypanosome development in the tsetse fly vector.

Not available

S-EPMC6312356 | biostudies-literature

Oxaboroles target trypanosome CPSF3

Oxaboroles target trypanosome CPSF3 - DDD85646 screen

PRJEB25882 | ENA

Function of Trypanosome brucei RBP10

PRJEB13058 | ENA

Oxaboroles target trypanosome CPSF3

Oxaboroles target trypanosome CPSF3 - SCYX-6759 screen