N6-threonylcarbamoyladenosine (t6A) is a universal tRNA modification essential for translational fidelity. The modification is installed at position 37 of ANN-decoding tRNAs (N is A, U, G or C) by transfer of a threonylcarbamoyl moiety from a pathway intermediate, catalyzed in bacteria by the TsaBD ...
ORGANISM(S): Escherichia coli