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UnknownPotential of Hyperthermophilic L-Asparaginase from <i>Thermococcus sibiricus</i> to Mitigate Dietary Acrylamide Assessed Using a Simplified Food System.
Not available
S-EPMC12111007 | biostudies-literature
TranscriptomicsGenome plasticity in Streptomyces: identification of 1 Mb TIRs in the S. coelicolor A3(2) chromosome
The chromosomes of several widely used laboratory derivatives of Streptomyces coelicolor A3(2) were found to have 1.06 Mb inverted repeat sequences at their termini (i.e. long-terminal inverted repeats; L-TIRs), which are 50 times the length of the 22 kb TIRs of the sequenced S. coelicolor strain M1...
ORGANISM(S): Streptomyces coelicolor 
2005-07-26 | E-GEOD-2994 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization Streptomyces coelicolor A3(2) strains
The chromosomes of several widely used laboratory derivatives of Streptomyces coelicolor A3(2) were found to have 1.06 Mb inverted repeat sequences at their termini (i.e. long-terminal inverted repeats; L-TIRs), which are 50 times the length of the 22 kb TIRs of the sequenced S. coelicolor strain M1...
ORGANISM(S): Streptomyces coelicolor 
2005-07-21 | E-SMDB-2740 | biostudies-arrayexpress
ProteomicsTotal proteome analysis of WT vs TRAP1 KO in HCT-116 and HEK-293T cells grown on different carbon sources.
The molecular chaperone TRAP1, the mitochondrial isoform of cytosolic HSP90, remains poorly understood with respect to its pivotal role in the regulation of mitochondrial metabolism. To characterize the impact of TRAP1 in maintaining the cellular proteome under different energy sources we carried ou...
ORGANISM(S): Homo sapiens (Human) 
2020-01-16 | PXD015828 | Pride
Oxidative phosphorylation Trap1 Mitochondrion Hsp90 Molecular chaperone 
TranscriptomicsRNA-seq comparison of fetal lung and cultured fetal lung derived organoids with pluripotent stem cell derived lung organoids
Underdeveloped lungs are the primary cause of death in premature infants, however, little is known about stem and progenitor cell maintenance during human lung development. In this study, we have identified that FGF7, Retinoic Acid and CHIR-99021, a small molecule that inhibits GSK3 to activate Wnt ...
ORGANISM(S): Homo sapiens 
2018-11-17 | E-MTAB-6023 | biostudies-arrayexpress
TranscriptomicsscRNA-seq of human fetal duodenal enteroids grown in EGF and/or NRG1
The purpose of this study was to interrogate the role of EGF-family ligands, in particular Epidermal Growth Factor (EGF) and Neuregulin 1 (NRG1), as human intestinal stem cell niche factors. An established duodenal enteroid line derived from a 20.2 week post conception biological specimen was expose...
ORGANISM(S): Homo sapiens 
2020-12-10 | E-MTAB-9720 | biostudies-arrayexpress
TranscriptomicsTranscriptional characterization of Human Lung Organoids (HLOs) using RNAseq
Human lung organoids (HLOs) were derived from human embryonic stem cell line H9 NIH registry #0062. Sequencing of HLOs was performed by the UM DNA Sequencing Core, using Illumina Hi-Seq platform and single-end 50 bp reads. The UM Bioinformatics Core downloaded the reads files from the Sequencing Cor...
ORGANISM(S): Homo sapiens 
2015-03-09 | E-MTAB-3339 | biostudies-arrayexpress
TranscriptomicsGene profile of mid-log phase of SD medium grown Candida albicans rhb1 gene deletion strain
Candida albicans is an opportunistic pathogenic yeast that is commensally found in variety of host niches. Rhb1 serves as an positive regulator of Tor1 kinase which is the central component of the TOR signaling in controlling several virulence factors. Here, we used microarray to determined changes ...
ORGANISM(S): Candida albicans 
2012-03-15 | E-GEOD-29128 | biostudies-arrayexpress
UnknownEndometrial Expression of Steroidogenic Factor 1 Promotes Cystic Glandular Morphogenesis.
Not available
S-EPMC4853565 | biostudies-literature
TranscriptomicsTranscription profiling of yeast over-expressing the meiosis-specific gene SPO13 during the mitotic cell cycle
Effect of overexpression of the meiosis-specific gene SPO13 during mitotic cell cycle
ORGANISM(S): Saccharomyces cerevisiae 
2008-07-31 | E-MEXP-1459 | biostudies-arrayexpress
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