Sort   by:  
 Page size 
UnknownConstruction of Methotrexate-Loaded Bi<sub>2</sub>S<sub>3</sub> Coated with Fe/Mn-Bimetallic Doped ZIF-8 Nanocomposites for Cancer Treatment Through the Synergistic Effects of Photothermal/Chemodynamic/Chemotherapy.
Not available
S-EPMC11783362 | biostudies-literature
TranscriptomicsTranscription profiling of the dynamic Innate Immune Responses in Human Bronchial Epithelial Cells against SARS-CoV and DOHV infection
Severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infection causes an immune-mediated disease. We have recently shown that SARS-CoV-induced epithelial Calu-3 cytokines could exacerbate and dampen host inflammatory and T cell responses, respectively, through modulating the functions...
ORGANISM(S): Homo sapiens 
2010-02-24 | E-GEOD-17400 | biostudies-arrayexpress
TranscriptomicsComparative dynamic transcriptome analysis (cDTA-seq) and total RNA-seq of ATP-analog sensitive Kin28 budding yeast
During transcription initiation, the TFIIH-kinase Kin28/Cdk7 marks RNA polymerase II (Pol II) by phosphorylating the C-terminal domain (CTD) of its largest subunit. Here we describe a structure-guided chemical approach to covalently and specifically inactivate Kin28 kinase activity in vivo. This met...
ORGANISM(S): Saccharomyces cerevisiae 
2016-06-16 | E-GEOD-83416 | biostudies-arrayexpress
TranscriptomicsLOC283731 promoter hypermethylation prognosticates survival after radiochemotherapy in IDH1 wild-type glioblastoma patients
MGMT promoter methylation status is currently the only established molecular prognosticator in IDH wild-type glioblastoma multiforme (GBM). Therefore, we aimed to discover novel therapy-associated epigenetic biomarkers. After enrichment for hypermethylated fractions using methyl-CpG-immunoprecipitat...
ORGANISM(S): Homo sapiens 
2016-03-10 | E-GEOD-74561 | biostudies-arrayexpress
UnknownBridging radiotherapy before chimeric antigen receptor T cells for B-cell lymphomas: an ILROG multicenter study.
Not available
S-EPMC12268022 | biostudies-literature
TranscriptomicsExpression profiles of microRNAs in gastric cancer
We analyzed expression profiles of microRNAs from 22 paired gastric cancer and normal tissues and identified differentially expressed microRNAs. RNA from paired normal and tumor specimens in 22 gastric cancer patients were extracted and treated for microRNA microarray analysis.
ORGANISM(S): Homo sapiens 
2011-04-21 | E-GEOD-28700 | biostudies-arrayexpress
TranscriptomicsCNV analysis of iPS cell lines and H2A.X knockout ES cell
It is well-known that embryonic stem cells (ESC) are much more sensitive to replication-induced stress than differentiated cells but the underpinning mechanisms are largely unknown. H2A.X, a minor variant of H2A, constitutes only 1-10% of the mammalian genome. H2A.X plays a well-known for role in t...
ORGANISM(S): Mus musculus 
2014-09-07 | E-GEOD-42266 | biostudies-arrayexpress
GenomicsH2A.X native ChIP-Seq in ESC and iPSC: Histone Variant H2A.X Mediated Epigenetic Mechanisms are Critical for Maintaining Genome Stability and Pluripotency in ES and iPS Cells
It is well-known that embryonic stem cells (ESC) are much more sensitive to replication-induced stress than differentiated cells but the underpinning mechanisms are largely unknown. H2A.X, a minor variant of H2A, constitutes only 1-10% of the mammalian genome. H2A.X plays a well-known for role in t...
ORGANISM(S): Mus musculus 
2014-09-07 | E-GEOD-42306 | biostudies-arrayexpress
Unknown30-Day Morbidity and Mortality of Bariatric Surgery During the COVID-19 Pandemic: a Multinational Cohort Study of 7704 Patients from 42 Countries.
Not available
S-EPMC8323543 | biostudies-literature
TranscriptomicsH2B mono-ubiquitylation facilitates fork stalling and recovery during replication stress by coordinating Rad53 activation and chromatin assembly
The influence of mono-ubiquitylation of histone H2B (H2Bub) on transcription via nucleosome reassembly has been widely documented. Recently, it has also been shown that H2Bub promotes recovery from replication stress; however, the underling molecular mechanism remains unclear. Here, we show that H2B...
ORGANISM(S): Saccharomyces cerevisiae 
2014-09-12 | E-GEOD-61030 | biostudies-arrayexpress
Sort   by:  
 Page size