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Overexpression of TSG101 causes cellular plasticity and development of adenosquamous mammary carcinoma
RNA-sequencing facilitates Quantitative Analysis of Wild Type and Tsg101 Transgenic cardiac transcriptomes
The protein Tsg101 plays an integral role extracellular vesicle formation and secretion from cells. We developed a mouse model with Tsg101 knockdown (Tsg101dAd). Visceral adipose tissue (VAT) was harvested from Tsg101dAD and Tsg101flfl mice fed high-fat diet to induce obesity or matched diet as non-...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-22 | PXD057436 | Pride
The mammalian Tumor Susceptibility Gene 101 (TSG101) encodes a protein with diverse functions that control the proliferation and survival of cells, but its role in malignant transformation has remained enigmatic. To study the pro-tumorigenic functions of TSG101, we developed a transgenic mouse model...
ORGANISM(S): Mus musculus 
2025-07-16 | GSE271036 | GEO
Tumor susceptibilty gene 101 (Tsg101) is a key member of the endosomal sorting complex required for transport (ESCRT), that has divergent roles in carcinogenesis, ubiquitination, endosomal trafficking, virus budding, cytokinesis, cell survival and proliferation. The goal of this study is to compare ...
ORGANISM(S): Mus musculus 
2019-02-27 | GSE126653 | GEO
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