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TranscriptomicsExpression profiling of murine hemopoietic cell survival
This SuperSeries is composed of the following subset Series: GSE18220: Expression profiling of murine hemopoietic cell survival on oligo arrays. GSE18221: Expression profiling of murine hemopoietic cell survival on cDNA arrays. Refer to individual Series
ORGANISM(S): Mus musculus 
2010-05-22 | E-GEOD-18222 | biostudies-arrayexpress
TranscriptomicsCTL-OA-OP human IT PF Bone - CompuGen H19K microarray study
Aims of study: (1) To identify systemic differences in osteoarthritic (OA) bone that contribute to OA pathogenesis. (2) Identify novel osteoporotic (OP) bone-related disease genes. Study involved comparison of trabecular bone extracted from the intertrochanteric (IT) region of the proximal femur (PF...
ORGANISM(S): Homo sapiens 
2008-01-14 | E-GEOD-8406 | biostudies-arrayexpress
Transcriptomicsangiogenesis course
This is a time course experiment with 4 - 6 slides per time point where all samples were hybridised to time zero. The microarray slides were scanned using a GenePix 4000B Scanner (Axon Instruments, Foster City, CA, USA). The â??SPOTâ?? software package (CSIRO) was used to identify spots and subtrac...
ORGANISM(S): Homo sapiens 
2010-06-05 | E-GEOD-779 | biostudies-arrayexpress
TranscriptomicsExpression profiling of murine hemopoietic cell survival on oligo arrays.
Deregulated cell survival programs are a classical hallmark of cancer. We have previously identified a serine residue (Ser585) in the beta-c subunit of the granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor that selectively and independently promotes cell survival. We now show that S...
ORGANISM(S): Mus musculus 
2010-05-22 | E-GEOD-18220 | biostudies-arrayexpress
TranscriptomicsExpression profiling of murine hemopoietic cell survival on cDNA arrays.
Deregulated cell survival programs are a classical hallmark of cancer. We have previously identified a serine residue (Ser585) in the beta-c subunit of the granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor that selectively and independently promotes cell survival. We now show that S...
ORGANISM(S): Mus musculus 
2010-05-22 | E-GEOD-18221 | biostudies-arrayexpress
TranscriptomicsGene expression microarray analysis of early oxygen-induced retinopathy (OIR)
Different inbred strains of rats differ in their susceptibility to OIR, an animal model of human retinopathy of prematurity. We examined gene expression profiles in Fischer 344 (F344, resistant to OIR) and Sprague Dawley (SD, susceptible to OIR) rats at the early time point of day 3 to identifying g...
ORGANISM(S): Rattus norvegicus 
2009-11-12 | E-GEOD-18998 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling shows different response to retinoids in estrogen-receptor positive and negative cells
This Series reports results of miRNA profiling of estrogen-receptor-positive (MCF7) and estrogen-receptor-negative (MDA-MB-231) cells. Retinoic Acid (RA) induces mir-21 in MCF-7 but not in MDA-MB-231 cells. MCF-7 and MDA-MB-231 cells were treated (or not) with retinoic acid (RA) and grown for either...
ORGANISM(S): Homo sapiens 
2010-05-21 | E-GEOD-18628 | biostudies-arrayexpress
TranscriptomicsEffects of retinoids on estrogen-receptor-positive and -negative breast carcinoma cells: mRNA profiling
The overall study explores differential sensitivity of estrogen-receptor-positive and -negative breast carcinoma cells to retinoids via gene expression and microRNA profiling in MCF7 and MDA-MB-231 cells. This Series reports results of transcriptional profiling of breast carcinoma cell lines compari...
ORGANISM(S): Homo sapiens 
2010-05-21 | E-GEOD-18390 | biostudies-arrayexpress
TranscriptomicsEffect of experimental stroke on meningeal gene expression and the influence of mast cells on these gene changes
Stroke is a leading cause of adult disability and death. Inflammation plays an important role in stroke pathology, but the factors which promote brain inflammation in this setting remain to be fully defined. Here we investigate the meninges, the membranes that envelop the brain, for a potential role...
ORGANISM(S): Mus musculus 
2014-07-31 | E-GEOD-51566 | biostudies-arrayexpress
TranscriptomicsAll trans-retinoic acid (ATRA) effect on triple negative (TNBC) and luminal (LumA/LumB) primary breast tumors
We performed whole genome gene expression microarrays on short-term cultures of mammary tumors deriving from diagnostic Tru-cut procedures of 16 patients in order to evaluate transcriptional response to the retinoid. Tissue slices were challenged with vehicle (DMSO) or ATRA 0.1åµm for 48 hours. The ...
ORGANISM(S): Homo sapiens 
2015-03-31 | E-MTAB-3313 | biostudies-arrayexpress
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