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Vascular remodeling in pulmonary arterial hypertension (PAH) involves proliferation and migration of endothelial and smooth muscle cells, leading to obliterative vascular lesions. Previous studies have indicated that the endothelial cell proliferation is quasi-neoplastic, with evidence of monoclonal...
ORGANISM(S): Homo sapiens 
This series contain mouse lung samples treated with Simvastatin and LPS and corresponded controls.
ORGANISM(S): Mus musculus 
Vascular remodeling in pulmonary arterial hypertension (PAH) involves proliferation and migration of endothelial and smooth muscle cells, leading to obliterative vascular lesions. Previous studies have indicated that the endothelial cell proliferation is quasi-neoplastic, with evidence of monoclonal...
ORGANISM(S): Homo sapiens 
This series contain unilateral mechanical ventilated canine lung samples.
ORGANISM(S): Canis familiaris 
Gene expression profiling of lung tissue from undiseased (NML), 'usual' emphysema (EML), and Alpha-1 Antitrypsin Deficiency-related emphysema (ADL).
ORGANISM(S): Homo sapiens 
RATIONALE: Mechanical ventilation (MV) is an indispensable therapy for critically ill patients with acute lung injury and the adult respiratory distress syndrome. However, the mechanisms by which conventional MV induces lung injury remain unclear. OBJECTIVES: We hypothesized that disruption of the g...
ORGANISM(S): Mus musculus 
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