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TranscriptomicsTranscription profiling of rat ovary in culture reveals interactions between progesterone and tumor necrosis factor-alpha in the regulation of primordial follicle assembly
Follicle assembly is the process by which groups or ‘nests’ of oocytes break down to form primordial follicles. The size of the primordial follicle pool is the major determinant of the reproductive lifespan of a female. Previously, progesterone (P4) has been shown to inhibit follicle assembly,...
ORGANISM(S): Rattus norvegicus 
2008-06-16 | E-GEOD-8238 | biostudies-arrayexpress
ProteomicsTumor necrosis factor α-induced protein 1 as a novel tumor suppressor through selective downregulation of CSNK2B blocks Nuclear Factor-κB activation in hepatocellular carcinoma
Background: Tumor necrosis factor α-induced protein 1 (TNFAIP1) is frequently downregulated in cancer cell lines and promotes cancer cell apoptosis. However, its role, clinical significance and molecular mechanisms in hepatocellular carcinoma (HCC) are unknown. Methods: The expression of TNFAIP1 in...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD016378 | Pride
Protein kinase casein kinase ii beta Hepatocellular carcinoma Nuclear factor-κb Tumor suppressor Tumor necrosis factor α-induced protein 1 
TranscriptomicsTranscription profiling of human primary foreskin fibroblasts treated with tumor necrosis factor alpha
Treatment of primary human foreskin fibroblasts with tumor necrosis factor alpha
ORGANISM(S): Homo sapiens 
2009-09-01 | E-MEXP-2186 | biostudies-arrayexpress
TranscriptomicsHPV16 E7 expression effect on expression profile mediated by tumor necrosis factor
Acute expression of E7 oncogene from HPV-16 or HPV-18 is sufficient to overcome tumor necrosis factor-alfa (TNF) cytostatic effect on primary human keratinocytes. In the present study we investigated the molecular basis of E7-induced TNF resistance through a comparative analysis of the effect of thi...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-17892 | biostudies-arrayexpress
ProteomicsMetabolic signature of HepaRG cells exposed to ethanol and tumor necrosis factor alpha to study ethanol-induced hepatotoxicity by LC-MS-based untargeted metabolomics
Metabolic signature of HepaRG cells exposed to ethanol and tumor necrosis factor alpha to study ethanol-induced hepatotoxicity by LC-MS-based untargeted metabolomics. Dataset contains .mzML files originating from an LC-QTOF (6530 for metabolomics & 6560 for lipidomics). HepaRG samples were exposed t...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-11-23 | MSV000090773 | MassIVE
GenomicsCharacterizing the profiles of histone markers in mouse adipocytes during insulin resistance
Insulin resistance is a sine qua non of Type 2 diabetes (T2D) and a frequent complication of multiple clinical conditions, including obesity, aging, and steroid use, among others. How such a panoply of insults can result in a common phenotype is incompletely understood. Furthermore, very little is k...
ORGANISM(S): Mus musculus 
2014-12-23 | E-GEOD-58491 | biostudies-arrayexpress
GenomicsMechanical stretch promotes invasion of lung cancer cells via activation of tumor necrosis factor-alpha
Mechanical stretch promotes invasion of lung cancer cells via activation of tumor necrosis factor-alpha
PRJNA883676 | ENA
GenomicsGene expression analysis of BeWo cells stimulated by tumor necrosis factor-alpha and insulin-like growth factor-I
Gene expression analysis of BeWo cells stimulated by tumor necrosis factor-alpha and insulin-like growth factor-I
PRJNA489858 | ENA
GenomicsDNA methylation analysis of BeWo cells stimulated by tumor necrosis factor-alpha and insulin-like growth factor-I
DNA methylation analysis of BeWo cells stimulated by tumor necrosis factor-alpha and insulin-like growth factor-I
PRJNA489857 | ENA
TranscriptomicsDistinct mechanisms of inadequate erythropoiesis induced by tumor necrosis factor alpha or malarial pigment
The role of infection in erythropoietic dysfunction is poorly understood. In children with P. falciparum malaria, the by-product of hemoglobin digestion in infected red cells (hemozoin) is associated with the severity of anemia which is independent of circulating levels of the inflammatory cytokine ...
ORGANISM(S): Homo sapiens 
2015-02-04 | E-GEOD-65577 | biostudies-arrayexpress
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