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TranscriptomicsXenobiotics shape the physiology and gene expression of the active human gut microbiome
The human gut is colonized by trillions of microorganisms that influence human health and disease through the metabolism of xenobiotics, including therapeutic drugs and antibiotics. The diversity and metabolic potential of the human gut microbiome have been extensively characterized, but it remains ...
ORGANISM(S): human gut metagenome 
2012-10-30 | E-GEOD-38151 | biostudies-arrayexpress
TranscriptomicsCharacterizing a model human gut microbiota composed of members of its two dominant bacterial phyla
The adult human gut microbial community is typically dominated by two bacterial phyla (divisions), the Firmicutes and the Bacteroidetes. Little is known about the factors that govern the interactions between their members. Here we examine the niches of representatives of both phyla in vivo. Finishe...
ORGANISM(S): Bacteroides thetaiotaomicron 
2010-05-22 | E-GEOD-14737 | biostudies-arrayexpress
TranscriptomicsTranscriptional profile of B. theta and E. rectale growing in the cecum of mice fed different diets
The adult human gut microbial community is typically dominated by two bacterial phyla (divisions), the Firmicutes and the Bacteroidetes. Little is known about the factors that govern the interactions between their members. Here we examine the niches of representatives of both phyla in vivo. Finishe...
ORGANISM(S): Eubacterium rectale 
2010-05-22 | E-GEOD-14709 | biostudies-arrayexpress
TranscriptomicsPredicting and manipulating drug inactivation by the human gut microbiome
The trillions of microorganisms in the human gastrointestinal tract are an underexplored aspect of pharmacology. Despite numerous examples of microbial effects on drug efficacy and toxicity, there is often an incomplete understanding of the underlying mechanisms. Here, we dissect the inactivation of...
ORGANISM(S): Eggerthella lenta DSM 2243 
2013-06-15 | E-GEOD-43919 | biostudies-arrayexpress
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