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GenomicsNeuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state
We report the application of single molecule-based sequencing technology for high-throughput genom-wide mapping of MeCP2 binding and DNA methylation in mouse brain and cerebellum respectively. We find a good correlation between MeCP2 occupancy and methyl-CpG density and depletion of MeCP2 binding at...
ORGANISM(S): Mus musculus 
2010-03-04 | E-GEOD-19786 | biostudies-arrayexpress
UnknownOptimizing the Use of Gene Expression Profiling in Early-Stage Breast Cancer.
Not available
S-EPMC5455310 | biostudies-literature
GenomicsComprehensive analysis of orphan CpG islands identifes novel promoters with conserved DNA methylation dynamics
We report the application of single molecule-based sequencing technology in combination with CXXC affinity purifcation (CAP-seq), MBD affinity purification (MAP-seq) and chromatin immunoprecipitation (ChIP-seq) to generate reciprocal methylation and chromatin modifcation maps in human and mouse. We ...
ORGANISM(S): Mus musculus 
2010-10-04 | E-GEOD-21442 | biostudies-arrayexpress
UnknownLong-term Pooled Safety Analysis of Palbociclib in Combination With Endocrine Therapy for HR+/HER2- Advanced Breast Cancer.
Not available
S-EPMC6449170 | biostudies-literature
UnknownLong-Term Pooled Safety Analysis of Palbociclib in Combination with Endocrine Therapy for Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: Updated Analysis with up to 5 Years of Follow-Up.
Not available
S-EPMC8100571 | biostudies-literature
UnknownClinical considerations of the role of palbociclib in the management of advanced breast cancer patients with and without visceral metastases.
Not available
S-EPMC5888946 | biostudies-literature
UnknownSystemic administration of an RNA binding and cell-penetrating antibody targets therapeutic RNA to multiple mouse models of cancer.
Not available
S-EPMC12375925 | biostudies-literature
GenomicsGenome-Wide Analysis of Hypodiploid Acute Lymphoblastic Leukemia

Hypodiploid acute lymphoblastic leukemia (ALL) is an aggressive form of leukemia characterized by multiple whole chromosomal losses and very poor outcome. Here we report an integrative genomic analysis that identifies multiple subtypes of hypodiploid ALL characterized by variation in the degree o...

phs000341.v1.p1 | EGA
UnknownA generalized epilepsy network derived from brain abnormalities and deep brain stimulation.
Not available
S-EPMC11933423 | biostudies-literature
GenomicsPCGP Ph-likeALL RNASeq - samples
DATA FILES FOR SJPhLike-RNASeq
EGAD00001001016 | EGA
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