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UnknownEffect of double dose oseltamivir on clinical and virological outcomes in children and adults admitted to hospital with severe influenza: double blind randomised controlled trial.

Objective

To investigate the validity of recommendations in treatment guidelines to use higher than approved doses of oseltamivir in patients with severe influenza.

Design

Double blind randomised trial.

Setting

Thirteen hospitals in Indonesia, Singapore, Thailand, and Vietnam.<...
S-EPMC3668094 | biostudies-literature
UnknownEffectiveness of Continuous Endotracheal Cuff Pressure Control for the Prevention of Ventilator-Associated Respiratory Infections: An Open-Label Randomized, Controlled Trial.

Background

An endotracheal tube cuff pressure between 20 and 30 cmH2O is recommended to prevent ventilator-associated respiratory infection (VARI). We aimed to evaluate whether continuous cuff pressure control (CPC) was associated with reduced VARI incidence compared with intermittent CPC.
S-EPMC9155610 | biostudies-literature
UnknownA community-based strategy to eliminate hepatitis C among people who inject drugs in Vietnam.

Background

Towards hepatitis C elimination among people who inject drugs (PWID), we assessed the effectiveness of a strategy consisting of a community-based respondent-driven sampling (RDS) as wide screening, a simplified and integrated hospital-based care, and prevention of reinfection supp...
S-EPMC10485672 | biostudies-literature
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