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TranscriptomicsmiRNAs expression in HepG2 hepatocellular carcinoma cell lines: Vector Control vs. Twist1, Bcl-2, and Twist1/Bcl-2 Transfected
miRNAs profiling of HepG2 cells comparing vector-control treated HepG2 cells with HepG2 cells transfected with Twist1, Bcl-2, and Twist1/Bcl-2 plasmids. Microarray analysis revealed a panel of miRNAs with significant differential expression among these four HCC cell lines.
ORGANISM(S): Homo sapiens 
2017-02-10 | GSE77501 | GEO
TranscriptomicsTwist1 gain-of-function studied in 2 normal gastric fibroblast lines
Primary human gastric normal fibroblast cultures (NL14 and NL32, repectivley) were establised from 2 gastrectomy specimens. Enforced expression (gain-of-function effect) of Twist1 in 2 gastric normal fibroblasts (NL14 and NL32) showed candidate target genes and CAF markers upregulated by Twist1.
ORGANISM(S): Homo sapiens 
2014-10-28 | GSE62739 | GEO
TranscriptomicsTranscription profiling of mouse Splenic DO11.10 cells ectopically expressing twist 1
The basic helix-loop-helix transcriptional repressor twist1, as an antagonist of nuclear factor κB (NF-κB)-dependent cytokine expression, is involved in the regulation of inflammation-induced immunopathology. We could show that twist1 is expressed by activated T helper (Th) 1 effector memory cells...
ORGANISM(S): Mus musculus 
2008-06-18 | E-GEOD-11533 | biostudies-arrayexpress
GenomicsHomo sapiens
miRNAs expression in HepG2 hepatocellular carcinoma cell lines: Vector Control vs. Twist1, Bcl-2, and Twist1/Bcl-2 Transfected
PRJNA310642 | ENA
TranscriptomicsTwist1 gain-of-function studied in 2 normal gastric fibroblast lines
Primary human gastric normal fibroblast cultures (NL14 and NL32, repectivley) were establised from 2 gastrectomy specimens. Enforced expression (gain-of-function effect) of Twist1 in 2 gastric normal fibroblasts (NL14 and NL32) showed candidate target genes and CAF markers upregulated by Twist1. Exp...
ORGANISM(S): Homo sapiens 
2014-10-28 | E-GEOD-62739 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression in response to genetic and growth factor manipulation of TWIST1 expression and function
In addition to their stem/progenitor properties, mesenchymal stem cells (MSCs) also exhibit various effector functions potent effector (angiogenic, anti-inflammatory, immune-modulatory) functions that are largely paracrine in nature. It is widely believed that effector functions underlie most of t...
ORGANISM(S): Homo sapiens 
2015-12-19 | E-GEOD-76158 | biostudies-arrayexpress
GenomicsHomo sapiens
Twist1 gain-of-function studied in 2 normal gastric fibroblast lines
PRJNA265063 | ENA
UnknownTargeting hexokinase 2 increases the sensitivity of oxaliplatin by Twist1 in colorectal cancer.
Not available
S-EPMC8435428 | biostudies-literature
UnknownMetastasis-associated in colon cancer-1 promotes vasculogenic mimicry in gastric cancer by upregulating TWIST1/2.
Not available
S-EPMC4484471 | biostudies-literature
TranscriptomicsTWIST1-induced microRNA-424 drives an intermediate epithelial-to-mesenchymal transition that opposes metastasis
Using a TWIST1-inducible epithelial-to-mesenchymal transition (EMT) model in HMLE cells, miRNA changes were profiled at different time points during an active EMT. This experiment includes a total of 12 samples consisting of 2 experimental groups at 2 matching time points (day 4, day 12), each with ...
ORGANISM(S): Homo sapiens 
2015-02-26 | E-GEOD-58560 | biostudies-arrayexpress
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