Sort   by:  
 Page size 
MetabolomicsDecreased abundance of type III secretion systeminducing signals in Arabidopsis mkp1 enhances resistance against Pseudomonas syringae
Genes encoding the virulence-promoting type III secretion system (T3SS) in phytopathogenic bacteria are induced at the start of infection, indicating that recognition of signals from the host plant initiates this response. However, the precise nature of these signals and whether their concentrations...
2014-06-24 | MTBLS95 | MetaboLights
MetabolomicsSerum metabolomic profile in children with type 1 diabetes mellitus: an exploratory targeted metabolomics study of candidate discriminatory features
Background: Type 1 diabetes mellitus (T1DM) is an increasingly common chronic disease caused by autoimmune damage to pancreatic beta cells. Metabolomic profiling may provide insights into metabolic disturbances associated with T1DM and identify candidate biomarkers. Methods: The study included 29 ch...
2026-09-22 | MTBLS15768 | MetaboLights
OtherAlterations in the interactome of serine/threonine protein phosphatase type-1 in atrial fibrillation patients.
Data from ProteomeXchange, PXD ID: PXD000697. Exiperiment: PP1_Mouse_raw_IgG, file: OR8_121211_NL_DC_PP1_Gel4_B_labelfree2.mzml. Published as part of J Am Coll Cardiol. 2015 Jan 20;65(2):163-73 . From the Abstract: {{i}} Cardiac lysates were coimmunoprecipitated with anti-PP1c antibody followed by ...
ORGANISM(S): Mus_musculus_viruses, Mouse 
GPM32320014437 | GPMDB
Resource Reanalysis 
ProteomicsThe C. elegans ASPP homolog APE-1 is a junctional Protein Phosphatase 1 modulator
Protein samples were analyzed by Multidimensional Protein Identification Technology (MudPIT), as described previously. Briefly, precipitated proteins were resuspended in 30uL of 100mM Tris pH 8.5 with 8M urea to denature proteins. Cysteines were reduced and alkylated prior to digestion with recombi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Caenorhabditis Elegans (ncbitaxon:6239) 
2022-02-04 | MSV000088781 | MassIVE
TranscriptomicsIntegrative transcriptome profiling of cognitive aging and its preservation through Ser/Thr protein phosphatase regulation
Environmental enrichment has been reported to delay or restore age-related cognitive deficits, however, a mechanism to account for the cause and progression of normal cognitive decline and its preservation by environmental enrichment is lacking. Using genome-wide SAGE-Seq, we provide a global assess...
ORGANISM(S): Mus musculus 
2015-06-24 | E-GEOD-43718 | biostudies-arrayexpress
TranscriptomicsMapping and characterization of promoter-binding sites of protein phosphatase 1
Protein phosphatase 1 (PP1) is a Ser/Thr phosphatase that has been implicated in many key cellular functions including transcriptional regulation. Due to its involvement these many processes, it becomes difficult to directly link PP1 to transcriptional regulation on the chromatin level as no direct ...
ORGANISM(S): Homo sapiens 
2015-06-17 | E-GEOD-54170 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of Rapamycin treatment in yeast cells lacking the Ptc1 protein phosphatase.
We are interested in the study of the already reported sensitivity of yeast cells lacking the type 1 protein phosphatase Ptc1 to the drug rapamycin. In order to carry out our studies, we analyzed the changes in the transcription profile that a short-term incubation with rapamycin (200 ng/mL) has in ...
ORGANISM(S): Saccharomyces cerevisiae 
2008-12-31 | E-GEOD-11530 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila tissue expressing phosphatase mutant eya shows that reducing phosphatase activity did not globally impair transcriptional output
Drosophila eye specification an development relies on a collection of transcription factors termed the retinal determination gene network (RDGN). Two members of this network, Eyes absent (EYA) and Sine oculis (SO), form a transcriptional complex in which EYA provides the transactivation function wh...
ORGANISM(S): Drosophila melanogaster 
2008-03-13 | E-GEOD-9538 | biostudies-arrayexpress
TranscriptomicsDisrupted interaction of transmembrane prostatic acid phosphatase and snapin will lead to prostate cancer
Disrupted interaction of transmembrane prostatic acid phosphatase and snapin will lead to prostate cancer
ORGANISM(S): Mus musculus 
2013-09-12 | E-MTAB-1191 | biostudies-arrayexpress
TranscriptomicsMethylation profiling by array of blood cells from patients with tartrate resistant acid phosphatase deficiency
The autosomal recessive immuno-osseus dysplasia spondyloenchondrodysplasia (SPENCD) is characterised by the variable combination of metaphyseal and vertebral bone lesions, immune dysfunction with features of both autoimmunity and immunodeficiency, and neurological involvement including developmental...
ORGANISM(S): Homo sapiens 
2011-05-05 | E-MEXP-2699 | biostudies-arrayexpress
Sort   by:  
 Page size