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UnknownmTORC2 promotes type I insulin-like growth factor receptor and insulin receptor activation through the tyrosine kinase activity of mTOR.
Not available
S-EPMC4816127 | biostudies-literature
UnknownThe insulin-like growth factor-1 receptor-targeting antibody, CP-751,871, suppresses tumor-derived VEGF and synergizes with rapamycin in models of childhood sarcoma.
Not available
S-EPMC3003871 | biostudies-literature
ProteomicsIdentification of phosphorylation sites in the IGF-1 Receptor
Although Insulin-like Growth Factor (IGF-1) signaling promotes tumor growth and cancer progression, IGF-1 Receptor-targeted therapies have shown poor clinical efficacy. The mechanistic basis for this is unclear as is our understanding of what distinguishes IGF-1R signaling from the closely related I...
ORGANISM(S): Homo sapiens (Human) 
2020-05-15 | PXD017644 | Pride
Tyr1131 Tyr1135 Tyr1136 Igf-1 Tyr125051 Igf-1 receptor 
MultiomicsBasal profile of receptor tyrosine kinase signaling network measured by ELISA
Not available
2015-09-23 | LDS-1123 | LINCS
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