U937 - OmicsDI

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Unknown (739)
Genomics (345)
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Proteomics (50)
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Organisms

Homo sapiens (301)
Aggregatibacter actinomycetemcomitans (36)
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Organisms

Homo sapiens (253)
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unidentified (1)

Repository

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geo (182)
biostudies-arrayexpress (125)
pride (36)
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Disease

Acute leukemia (7)
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Leukemia (3)
HHV-6B infected (2)
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Disease free (2)
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B-cell chronic lymphocytic leukemia (1)
Acute promyelocytic leukemia (1)
Cervix carcinoma (1)
Liver cancer (1)
Myeloid leukemia (1)
Nephrolithiasis (1)
Pancreatic ductal adenocarcinoma (1)

Technology Type

Mass Spectrometry (36)
Shotgun proteomics (22)
Affinity purification coupled with mass spectrometry proteomics (6)
Data-dependent acquisition (6)
Bottom-up proteomics (5)
Gel-based experiment (2)
SWATH MS (2)
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Instrument Platform

Axon GenePix 4000B scanning hardware (5)
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Illumina HiSeq 2500 (3)
Illumina HiSeq 2000 (2)
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Orbitrap Fusion Lumos (2)
Q Exactive Plus (2)
TripleTOF 5600 (2)
ArrayWoRx Multi-Format Reader [Applied Precision] (1)
Illumina NovaSeq X (1)
BGISEQ-500 (1)
NextSeq 550 (1)
Illumina NovaSeq 6000 (1)
Illumina HiSeq 4000 (1)
TimsTOF SCP (1)

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2008 (27)
2025 (24)
2010 (24)
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2014 (22)
2013 (22)
2015 (21)
2021 (20)
2026 (19)
2023 (19)
2017 (19)
2022 (18)
2009 (17)
2016 (15)
2018 (12)
2011 (11)
2020 (10)
2012 (10)
2019 (9)
2006 (7)
2007 (5)
2004 (5)
2005 (1)

First Public Date

2014 (69)
2024 (38)
2025 (30)
2023 (29)
2022 (22)
2021 (19)
2026 (18)
2019 (16)
2017 (15)
2015 (15)
2018 (12)
2020 (11)
2016 (7)
2013 (4)

Classification

bacteria (2)

Study type

Transcription profiling by array (80)
RNA-seq of coding RNA (8)
ChIP-chip by array (6)
ChIP-seq (6)
ChIP-chip by tiling array (5)
Methylation profiling by array (5)
Unknown experiment type (2)
Transcription profiling by tiling array (2)
4C (2)
RNA-seq of total RNA (2)
Transcription profiling by SAGE (1)
Cell line - High-throughput sequencing (1)
Transcription profiling by RT-PCR (1)
Comparative genomic hybridization by array (1)
Other (1)
MicroRNA profiling by array (1)
RNA-seq of coding RNA from single cells (1)

Release Date

2021 (66)
2020 (64)
2022 (57)
2018 (56)
2016 (53)
2019 (51)
2025 (48)
2014 (46)
2023 (43)
2015 (43)
2024 (42)
2010 (41)
2017 (40)
2013 (39)
2011 (30)
2012 (29)
2009 (26)
2008 (20)
2005 (13)
2007 (11)
2006 (9)
2004 (7)
2026 (6)
1999 (6)
2001 (4)
2000 (4)
1998 (4)
2003 (3)
2002 (3)

Lab affiliation

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA (3)
Barnett Institute of Chemical and Biological Analysis, Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Ave., Boston, Massachusetts 02115, United States (2)
Director of the Robert H. Lurie Comprehensive Cancer Center of Northwestern University and the Jesse, Sara, Andrew, Abigail, Benjamin and Elizabeth Lurie Professor of Oncology in the Departments of Medicine and Biochemistry and Molecular Genetics. (2)
NIAID, NATIONAL INSTITUTES OF HEALTH (2)
1Department of Chemistry and Sarafan Chem-H, Stanford University, Stanford, CA 94305, USA 2Howard Hughes Medical Institute, Stanford, CA 94305, USA (1)
CBIO, de Duve institute, UCLouvain, Belgium (1)
CRCHUM-Centre Hospitalier de l'Université de Montréal, Montréal, QC H2X 0A9, Canada. (1)
DZNE Munich Neuroproteomics, Feodor-Lynen-Str. 17, 81377 München, Germany (1)
Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Vienna, Austria. Joint Metabolome Facility, University of Vienna and Medical University of Vienna, Vienna, Austria. (1)
Department of Analytical Chemistry, University of Vienna (1)
Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv university, Tel Aviv, Israel (1)
Department of Innovative Technologies in Medicine & Dentistry, University of "G. d'Annunzio" of Chieti-Pescara, Chieti, Italy (1)
Department of Proteomics and Signal Transduction Max Planck Institute of Biochemistry Germany (1)
Department of Vascular Biology and Thrombosis Research, Centre of Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstrasse 17, A-1090 Vienna, Austria (1)
Deprtment of Biology, Technion - Israel Institue of Technology, Haifa, Israel (1)
Dipartimento di Scienze e Tecnologie Ambientali Biologiche e Farmaceutiche Università degli Studi della Campania“Luigi Vanvitelli” (1)
Division of Cancer and Genetics, Department of Haematology, Cardiff University , Cardiff, UK (1)
Drug Delivery, Disposition and Dynamics Theme, Monash Institute of Pharmaceutical Science, Monash University, Parkville, Victoria, Australia (1)
Experimental Systems Immunology, Max-Planck Institute of Biochemistry, Martinsried, Germany (1)
Functional Cellular Networks Section Laboratory of Immune System Biology National Institute of Allergy and Infectious Diseases National Institutes of Health (1)
Functional Proteomics, ICR (1)
Karolinska Institutet, Department of Oncology-Pathology (1)
Lady Davis Institute, McGill University (1)
Medical Proteomics Unit, Office for Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand (1)
Molecular Pharmacology Program, Sloan Kettering Institute, Tow Center for Developmental Oncology, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, and Doctor of Medicine Program, Weill Cornell Medicine (1)
Northwestern University Proteomics Core (1)
Serrano lab, Systems and Synthetic Biology programme, Centre for Genomic Regulation (CRG) (1)
The Jackson Laboratory for Genomic Medicine, 10 Discovery Drive, Farmington, CT 06032, USA (1)
Universita Della Campania Luigi Vanvitelli (1)
University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry (1)

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Identification of latent tuberculosis infection-related microRNAs in human U937 macrophages expressing Mycobacterium tuberculosis Hsp16.3

Latent tuberculosis infection (LTBI) relies on a homeostasis of macrophages and Mycobacterium tuberculosis (Mtb). The small heat shock protein, Mtb Hsp16.3 (also known as latency-associated antigen), plays an important role in Mtb persistence within macrophages. However, the mechanism of LTBI remain...

ORGANISM(S): Homo sapiens

2014-03-17 | E-GEOD-54630 | biostudies-arrayexpress

The differentiation/retrodifferentiation program of human U937 leukemia cells is accompanied by changes of VCP/p97

A possible functional role of VCP/p97 during differentiation of U937 cells was addressed by siRNA-targeting of VCP/p97. Functional changes in VCP-siRNA-transfected cells following phorbol ester-induced monocytic differentiation have been examind by DNA microarray analysis. Cells transfected with the...

ORGANISM(S): Homo sapiens

2010-06-29 | E-GEOD-9821 | biostudies-arrayexpress

DNA methylation analysis of the U937 cell line

DNA methylation profiling of gene promoters in the human myeloid cell line U937. Bisulphite converted DNA from wildtype U937 cells was hybridised to the Illumina Infinium HumanMethylation27 BeadChip to determine the methylation pattern of the U937 cell line.

ORGANISM(S): Homo sapiens

2014-09-26 | E-GEOD-60734 | biostudies-arrayexpress

Transcription profiling of human U927 cells polysomal and cytoplasmic RNA before and after PMA stimulation

Human histomonocytic U937 cells exhibit macrophage-like properties after phorbol ester stimulation. Accumulating evidence demonstrated that remarkable number of transcripts changed in their amount at total RNA levels. However, post-transcriptional regulation has not been fully elucidated in this m...

ORGANISM(S): Homo sapiens

2008-06-11 | E-GEOD-1783 | biostudies-arrayexpress

Gene expression changes upon knockdown of DEK in the U937 cell line

Gene expression profiling of U937 cells upon knockdown of the DEK oncogene by two different shRNAs (shDEK14 and shDEK17). The DEK oncogene was knocked down by shRNA to study the changes in gene expression.

ORGANISM(S): Homo sapiens

2014-09-26 | E-GEOD-60732 | biostudies-arrayexpress

Genes regulated after knock-down of Pirin in U937 cells

Pirin (PIR) is a putative transcriptional regulator whose expression is silenced in cells bearing the AML1/ETO and PML/RAR leukemogenic fusion proteins and is significantly repressed in a large proportion of acute myeloid leukemias. PIR expression increases during in vitro myeloid differentiation of...

ORGANISM(S): Homo sapiens

2009-12-10 | E-GEOD-16798 | biostudies-arrayexpress

Transcription profiling of human U937 lymphoma cells treated with paeony root (Paeoniae radix) (time series)

Paeoniflorin (PF) isolated from paeony root (Paeoniae radix) has been used as an herbal medicine in East Asis for its anti-allergic, anti-inflammatory, and immunoregulatory effects. PF is known to be a chemical heat shock protein (HSP) inducer. The effects on the gene expression in human lymphoma U9...

ORGANISM(S): Homo sapiens

2008-06-16 | E-GEOD-8228 | biostudies-arrayexpress

Transcription profiling of human U937 leukemia cells in apoptosis induced by ansimycin

Anisomycin is known as a potent apoptosis inducer by activating JNK/SAPK and inhibiting protein synthesis during translation. However, only few details are known on the mechanism of apoptosis induced by this compound. Genes in apoptosis induced by anisomycin in human leukemia U937 cells were investi...

ORGANISM(S): Homo sapiens

2008-06-16 | E-GEOD-8229 | biostudies-arrayexpress

U937 cells: differentiating vs. undifferentiated

Gene-expression changes in U937 cells undergoing monocytic differentiation with TPA treatment Keywords: differentiation treatment The promonocytic U937 cell line was maintained at 37C in RPMI 1640 medium (Mediatech) supplemented with 10% fetalclone (HyClone) under a 5% CO2, 95% air atmosphere. U937 ...

ORGANISM(S): Homo sapiens

2010-06-20 | E-GEOD-10560 | biostudies-arrayexpress

Microarray profiling of monocytic differentiaion reveals miRNA-mRNA intrinsic correlation (gene expression)

Since the expression profile of miRNAs is specific in different tissues or under different physiological conditions, the correlations between miRNAs and mRNAs could vary under different biological circumstances. This is a study also used expression profiles of miRNA and mRNA during monocytic differe...

ORGANISM(S): Homo sapiens

2012-02-02 | E-GEOD-26377 | biostudies-arrayexpress

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