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TranscriptomicsRIP-Seq of An Integrated Signaling Network Controls P-Bodies Dynamics and mRNA Translation in Human Glioblastoma
Processing (P)-bodies are cytoplasmic membrane-less condensates including translationally repressed mRNAs and proteins involved in the mRNA decay machinery. The mechanisms underlying P-bodies nucleation and mRNA decay have been largely described. However, the impact of signaling networks in P-bodies...
ORGANISM(S): Homo sapiens 
2025-03-30 | E-MTAB-14331 | biostudies-arrayexpress
UnknownOsHrd3 is necessary for maintaining the quality of endoplasmic reticulum-derived protein bodies in rice endosperm.
Not available
S-EPMC4507767 | biostudies-literature
UnknownNuclear p62 condensates stabilize the promyelocytic leukemia nuclear bodies by sequestering their ubiquitin ligase RNF4.
Not available
S-EPMC11513912 | biostudies-literature
ProteomicsMlf Mediates Proteotoxic Response via Formation of Cellular Foci for Protein Folding and Degradation
Myeloid leukemia factor 1 (Mlf1) was identified as a proto-oncoprotein that affects hematopoietic differentiation in humans. However, its cellular function remains elusive, spanning roles from cell cycle regulation to modulation of protein aggregate formation and participation in ciliogenesis. Given...
ORGANISM(S): Giardia intestinalis (Giardia lamblia) 
2025-05-13 | PXD050586 | Pride
: myeloid leukemia factor Giardia Protein quality control Ubiquitin-rich bodies Stress response Proteasome 
GenomicsCell Type-Specific DNA Methylation at Intragenic CpG Islands in the Immune System (MAP-Seq and ChIP-Seq data)
Human and mouse genomes contain a similar number of CpG islands (CGIs), which are discrete CpG-rich DNA sequences associated with transcription start sites. In both species, about 50% of all CGIs are remote from annotated promoters, but nevertheless often have promoter-like features. To document the...
ORGANISM(S): Mus musculus 
2011-05-23 | E-GEOD-25688 | biostudies-arrayexpress
UnknownHsp40 proteins phase separate to chaperone the assembly and maintenance of membraneless organelles.
Not available
S-EPMC7733851 | biostudies-literature
UnknownOn the nature of the Cu-rich aggregates in brain astrocytes.
Not available
S-EPMC5198742 | biostudies-literature
UnknownThe herpes simplex virus immediate-early ubiquitin ligase ICP0 induces degradation of the ICP0 repressor protein E2FBP1.
Not available
S-EPMC3067832 | biostudies-literature
UnknownTDP-43 pathology in a patient carrying G2019S LRRK2 mutation and a novel p.Q124E MAPT.
Not available
S-EPMC3906605 | biostudies-literature
ProteomicsSINE retrotransposons link replication timing with higher-order genome organization by recruiting H2Bub to gene body
The mammalian genome is spatially segregated into euchromatin-associated A and heterochromatin-associated B compartments that replicate early, and late in S-phase respectively. The molecular links connecting higher-order genome organization with replication timing, however, remain unclear. Here, we ...
ORGANISM(S): Mus Musculus (mouse) 
2025-08-27 | PXD067536 | JPOST Repository
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