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TranscriptomicsTranscription profiling of human bone marrow-derived sesenchymal stem cells with prolonged life span vs life span after neuronal induction
Primary culture of marrow-derived mesenchymal cells vs marrow-derived MSCs with a prolonged life span vs MSCs with a prolonged life span after neuronal induction.
ORGANISM(S): Homo sapiens 
2008-06-19 | E-GEOD-2110 | biostudies-arrayexpress
TranscriptomicsEpiphyseal cartilage
Chondrocytes from extra fingers exhibited a high proliferative capacity: the cells reached to population doublings (PD) 30-35 within 4 weeks before replicative senescence. The propagated cells formed hyaline cartilage at 2 weeks after subcutaneous implantation of NOD/Scid/IL-2 receptor gamma knock o...
ORGANISM(S): Homo sapiens 
2011-03-22 | E-GEOD-17368 | biostudies-arrayexpress
TranscriptomicsAn analysis of genomic structural alteration in three human ES cell lines.
To elucidate frequencies of genomic structural alterations, we performed an analysis using a SNP genotyping array (Illumina HumanCytoSNP-12 v2.1 DNA Analysis BeadChip Kit) for three human ES cell lines, namely, SEES-1, SEES-2, and SEES-3. Samples were collected after 4 to 60 passages to detect struc...
ORGANISM(S): Homo sapiens 
2015-05-20 | E-GEOD-54576 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human cell types to identify genes responsible for cardiomyogenic differentiation
We performed the GeneChip analysis to identify multiple extracellular determinants such as cytokines, cell membrane-bound molecules, and matrix responsible for cardiomyogenic differentiation, and evaluated the statistical significance of differential gene expression by the NIA array analysis (http:/...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-8481 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse placenta cells
The placenta is considered one of the candidate cell sources in cellular therapeutics because of a large number of cells and heterogenous cell population with myogenic potentials. We first analyzed myogenic potential of cells obtained from six parts of the placenta, i.e., umbilical cord, amniotic ep...
ORGANISM(S): Homo sapiens 
2008-06-20 | E-GEOD-11510 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human chorionic villi cells co-culutured with fetal cardiomyocytes
In the chorionic villi of placenta, trophoblasts and endothelial cells are present, and moreover mesenchymal cells (stromal cells) can be obtained. We generated cells with the mesenchymal phenotype from the chorionic mesoderm, and showed that: a) physiologically functioning cardiomyocytes were trans...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7021 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse Pooh cell line (POU5F1/Oct-4/3 overexpressing human)
POU5F1 (more commonly known as Oct-4/3) is one of the stem cell markers and affects direction of differentiation in embryonic stem cells. To investigate whether cells of mesenchymal origin acquire embryonic phenotype, we generated a human cell line of mesodermal origin with overexpression of the ch...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-8113 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human cultured scleral cells
The sclera maintains and protects the eye ball, which receives visual inputs. The aim of this study is to identify characteristics of the human sclera as one of the connective tissues derived from the neural crest and mesoderm. We have here demonstrated microarray data of cultured human scleral cell...
ORGANISM(S): Homo sapiens 
2008-06-11 | E-GEOD-10934 | biostudies-arrayexpress
TranscriptomicsTranscriptome profile in the human synovial MSC-aggregates
One of strategies to regenerate cartilage defect is transplantation of mesenchymal stem cells (MSCs). Improvements of therapeutic potential of MSCs are needed to achieve successful cartilage regeneration by transplantation of a limited number of cells. Aggregated culture is a popular method in ES an...
ORGANISM(S): Homo sapiens 
2012-05-12 | E-GEOD-31980 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse EMT-induced and non-induced cells
The conversion of an epithelial cell to a mesenchymal cell is critical to vertebrate embryogenesis and a defining structural feature of organ development, such as forming fibroblasts in injured tissues, or in initiating metastases in epithelial cancer. From a general perspective, EMT is about disagg...
ORGANISM(S): Mus musculus 
2011-08-12 | E-GEOD-31359 | biostudies-arrayexpress
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