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The accumulatiob of cancer-associated fibroblasts in tumours correlates with poor prognosis across cancer types including oesophageal adenocarcinoma. In this study we examined the proteomic profile of cancer-associated fibroblasts compared to normal fibroblasts.
ORGANISM(S): Homo sapiens (Human) 
2018-08-13 | PXD005444 | Pride
Cancer associated fibroblasts characterized by an myofibroblastic phenotype play a major role in the tumour microenvironment, being associated with poor prognosis. We found that this cell population is made in part by senescent fibroblasts in vivo. As senescent fibroblasts and myofibroblasts have be...
ORGANISM(S): Homo sapiens 
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