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TranscriptomicsscRNAseq datasets of human brain organoids generated for the manuscript "Morphodynamics of human early brain organoids
Here we have provided scRNAseq datasets of unguided human brain organoids. The organoids were sequenced as a 1) Timecourse, 2) With different extracellular matrix treatments, 3) chemical treatment and 4) from organoids ere generated with a gene knockout cell line. Brain organoids enable the mechanis...
ORGANISM(S): Homo sapiens 
2025-04-30 | E-MTAB-15057 | biostudies-arrayexpress
ProteomicsMicrocephaly-like phenotype triggered by novel reassortant and prototypic Oropouche Virus strains in brain organoids (60 day Unguided Organoids)
DDA based proteomic analysis of 60 day Cerebral Brain Organoids
ORGANISM(S): Homo sapiens (Human) 
2026-05-28 | PXD072981 | Pride
Unguided brain organoids 
ProteomicsMulti-omic analysis of guided and unguided forebrain organoids
Neural organoids are invaluable model systems for studying neurodevelopment and neurological diseases. For this purpose, reproducible differentiation protocols are needed that minimize inter-organoid variability whilst generating neural organoids that physiologically resemble the brain area of inter...
ORGANISM(S): Homo sapiens (Human) 
2026-02-25 | PXD048559 | Pride
Human Organoids Orbitrap exploris Forebrain Sialylation Phosphorylation 
TranscriptomicsBulk RNA-seq comparing brain organoids in vitro systems treated or not with 3,3’-5-triiodothyronine (T3)
This experiment aims to define DGE when hiPSC derived brain organoids are exposed for long (chronic) or short (pulse) time to T3. Additionally, a comparison regarding T3 responsive genes can be assessed for two different brain organoids systems: cerebral organoids (CO) and Neural Stem Cell derived O...
ORGANISM(S): Homo sapiens 
2026-05-30 | E-MTAB-17066 | biostudies-arrayexpress
ProteomicsMorpho-metabolic monitoring of individualized human cerebral organoid growth and quality in a non-destructive platform
DIA based proteomic analysis of 60 day Cerebral Brain Organoids
ORGANISM(S): Homo sapiens (Human) 
2026-05-28 | PXD076392 | Pride
Unguided brain organoids 
GenomicsMulti-omic analysis of guided and unguided forebrain organoids reveal differences in cellular composition and metabolic profiles
Multi-omic analysis of guided and unguided forebrain organoids reveal differences in cellular composition and metabolic profiles
PRJNA1067622 | ENA
TranscriptomicsMulti-omic analysis of guided and unguided forebrain organoids reveal differences in cellular composition and metabolic profiles
Neural organoids are invaluable model systems for studying neurodevelopment and neurological diseases. For this purpose, reproducible differentiation protocols are needed that minimize inter-organoid variability whilst generating neural organoids that physiologically resemble the brain area of inter...
ORGANISM(S): Homo sapiens 
2026-03-04 | GSE253889 | GEO
GenomicsscRNAseq datasets of human brain organoids generated for the manuscript \"Morphodynamics of human early brain organoids
scRNAseq datasets of human brain organoids generated for the manuscript \"Morphodynamics of human early brain organoids
PRJEB88702 | ENA
ProteomicsComprehensive secretome and proteome analysis for human fetal brain self-organized organoids
To understand whether the intrinsic capacity of the fetal brain in vitro self-organizes into organoids (FeBOs) to secrete a tissue-like “matrisome” is linked to the maintenance of cell-to-cell organization and integrity, we compared the secretome of intact FeBOs and FeBO-derived neurospheres. We als...
ORGANISM(S): Homo sapiens (Human) 
2024-01-08 | PXD047075 | Pride
Human fetal brain Proteomics Tissue-derived organoids Lc-ms/ms 
UnknownPreconfigured neuronal firing sequences in human brain organoids.
Not available
S-EPMC12912721 | biostudies-literature
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