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Sub-Saharan Africa currently experiences an unprecedented wave of urbanization, which has important consequences for health and disease patterns. This study aimed to investigate and integrate the immune and metabolic consequences of rural or urban lifestyles and the role of nutritional changes assoc...
2021-06-22 | MTBLS2267 | MetaboLights

Gut commensal bacteria promote host reproduction by modulating metabolism and nutrition, but the molecular mechanisms by which microbes regulate reproduction remain unclear. Here, we show that gut commensal bacteria promote host reproduction by providing amino-acid methionine, which controls the ...

2025-06-22 | MTBLS12470 | MetaboLights
Atmospheric particulate matter (PM) is a recognized risk factor for the global burden of disease in human populations. We are presenting here the application of toxicogenomics in the evaluation of the toxic effects of organic content of atmospheric particle matter (PM), from urban and rural environm...
ORGANISM(S): Danio rerio 
Human lung cells (BEAS-2B) were exposed to either liquid suspensions of 125 ug/mL urban particulate matter (NIST, SRM 1648a) or growth media only control for 24 hours at 37C, 5% CO2. We have explored the changes in expression level and subcellular abundance of key proteins involved in cellular respo...
ORGANISM(S): Homo sapiens (Human) 
2026-02-10 | PXD052537 | Pride
Transcriptome profiling of three DDT resistant strains of Anopheles gambiae in Cameroon (Gare, Messa and Nkolondom- 2 M forms and one S form) compared to the susceptible strain Ngousso (M form) and Kisumu (S form). S-form is distributed across sub-Saharan Africa and breeds mostly in association with...
ORGANISM(S): Anopheles gambiae 
Molecular epidemiological study of M. tuberculosis strains from urban and slum areas in Nairobi
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