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ProteomicsDepletion of Keratin8 affects tumorigenic potential of A431 cells via altering multiple signaling pathways
Keratins are the largest subgroup of intermediate filament proteins which are expressed in a tissue specific and differentiation state dependent manner. Apart from their mechanical functions, they have been shown to perform various regulatory roles. Most of these functions have been studied on ker...
ORGANISM(S): Homo sapiens (Human) 
2018-02-27 | PXD007206 | Pride
Human Quantitative proteomics Tmt Skin-scc Keratin 8 
ProteomicsQuantitative phosphoproteomic analysis reveals system-wide signaling pathways regulated by site-specific phosphorylation on Keratin-8 in skin squamous cell carcinoma derived cell-line
The epithelial specific keratin pair, Keratin 8/18 (K8/18), has been reported to be aberrantly expressed in squamous cell carcinoma (SCC) which is also correlated with increased invasiveness and poor prognosis. A Majority of Keratin 8 (K8) functions are governed by its phosphorylation at Serine73 (...
ORGANISM(S): Homo sapiens (Human) 
2018-07-05 | PXD005301 | Pride
Keratin 8 phosphorylation Tmt based quantitative phosphoproteomics Human epidermoid carcinoma cell-line 
UnknownAcute and Chronic Electroconvulsive Seizures (ECS) Differentially Regulate the Expression of Epigenetic Machinery in the Adult Rat Hippocampus.
Not available
S-EPMC5043647 | biostudies-literature
TranscriptomicsNext Generation Sequencing identifies Cdh11 and Mrc1 as novel translational biomarkers of kidney fibrosis
Chronic kidney disease (CKD) is the gradual, asymptomatic loss of kidney function and current tests only identify it when significant loss has already happened. Using RNA sequencing in a mouse model of folic acid (FA) induced nephropathy, here we report the identification of 10 genes that track kidn...
ORGANISM(S): Mus musculus 
2015-10-23 | E-GEOD-65267 | biostudies-arrayexpress
TranscriptomicsTo examine the influence of the early stress of maternal separation on the hippocampal transcriptome in young adulthood
In this study, we examined the consequences of the early stress (ES) of maternal separation on hippocampal gene expression in young adulthood. Young adult (2 months old) ES animals exhibit hippocampal transcriptome changes with a significant regulation of genes associated with intracellular signalin...
ORGANISM(S): Rattus norvegicus 
2013-10-11 | E-GEOD-29412 | biostudies-arrayexpress
UnknownNutraceutical properties of cumin residue generated from Ayurvedic industries using cell line models.
Not available
S-EPMC5147708 | biostudies-literature
UnknownUnliganded thyroid hormone receptor alpha1 impairs adult hippocampal neurogenesis.
Not available
S-EPMC4177098 | biostudies-literature
UnknownInhibition of Bacterial Adhesion and Antibiofilm Activities of a Glycolipid Biosurfactant from Lactobacillus rhamnosus with Its Physicochemical and Functional Properties.
Not available
S-EPMC8698754 | biostudies-literature
UnknownFunctional and Structural Characterization of Pediococcus pentosaceus-Derived Biosurfactant and Its Biomedical Potential against Bacterial Adhesion, Quorum Sensing, and Biofilm Formation.
Not available
S-EPMC8614858 | biostudies-literature
UnknownIncreased susceptibility of aging kidney to ischemic injury: identification of candidate genes changed during aging, but corrected by caloric restriction.
Not available
S-EPMC2758575 | biostudies-literature
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