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UnknownComparative effectiveness of contact tracing interventions in the context of the COVID-19 pandemic: a systematic review.
Not available
S-EPMC9932408 | biostudies-literature
GenomicsBase-resolution detection of N4-methylcytosine in genomic DNA using 4mC-TAB-seq
N4-methylcytosine is a major DNA modification integral to restriction-modification (R-M) systems in bacterial genomes. Here we describe 4mC-Tet-Assisted Bisulfite-sequencing (4mC-TAB-seq), a method that accurately and rapidly reveals the genome-wide locations of N4-methylcytosines at single-base res...
ORGANISM(S): Caldicellulosiruptor kristjanssonii 
2015-07-11 | E-GEOD-63371 | biostudies-arrayexpress
TranscriptomicsExpression data for human retinal pigment epithelium (RPE)/choroid - early age-related macular degeneration (AMD) and control samples
Purpose: Age-related degeneration (AMD) is a major cause of blindness in developed countries. The molecular pathogenesis of early events in AMD is poorly understood. We investigated differential gene expression in samples of human retinal pigment epithelium (RPE)/choroid from early AMD and control m...
ORGANISM(S): Homo sapiens 
2013-12-23 | E-GEOD-50195 | biostudies-arrayexpress
UnknownClinical outcomes in patients with relapsed/refractory FLT3-mutated acute myeloid leukemia treated with gilteritinib who received prior midostaurin or sorafenib.
Not available
S-EPMC9151663 | biostudies-literature
TranscriptomicsExpression profiling of HCC
61 human HCCs were analyzed for genome-wide gene expression. Samples were collected at two sites in Germany, Heidelberg (HD) and Hannover (N). The Heidelberg Collection include 40 independent HCC: 19 liver resections and 17 explant liver specimen (4 not determined); median age at surgery was 57 year...
ORGANISM(S): Homo sapiens 
2013-09-05 | E-GEOD-50579 | biostudies-arrayexpress
TranscriptomicsRate, spectrum, and evolutionary dynamics of spontaneous epimutations
Stochastic changes in cytosine methylation are a source of heritable epigenetic and phenotypic diversity in plants. Using the model plant Arabidopsis thaliana, we derive robust estimates of the rate at which methylation is spontaneously gained (forward epimutation) or lost (backward epimutation) at ...
ORGANISM(S): Arabidopsis thaliana 
2015-05-13 | E-GEOD-64463 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae treated with phenelzine results in a perturbation in the system leads to period doubling
Perturbation of the gated-synchrony system in yeast with phenelzine, an antidepressant drug used in the treatment of affective disorders in humans, leads to a rapid lengthening in the period of the genome-wide transcriptional oscillation. The effect is a concerted, genome-scale change in expression ...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-16 | E-GEOD-9302 | biostudies-arrayexpress
TranscriptomicsRenal Dysfunction in the Setting of Massive Hepatic Necrosis: A Network-based Analysis in a Mouse
To date, no published reports (human or animal) have examined the impact of acute liver failure on global gene expression profiles in remote organ systems like the kidney. In this study, we have characterized a model of acute kidney injury (AKI) using two highly-accurate techniques for assessing re...
ORGANISM(S): Mus musculus 
2012-01-01 | E-GEOD-24971 | biostudies-arrayexpress
UnknownReference-based comparison of adaptive immune receptor repertoires.
Not available
S-EPMC9421535 | biostudies-literature
UnknownProtein NMR structures refined with Rosetta have higher accuracy relative to corresponding X-ray crystal structures.
Not available
S-EPMC4129517 | biostudies-literature
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