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Transcription profiling of mouse skin carcinogenesis in FVB/N and Tg.Ac mice

Female FVB/N and Tg.Ac (hemizygotes) mice 3-5 weeks of age were purchased from Harlan UK and Taconic UK, respectively. The mice were contained in an isolator and maintained at 19C with 50% relative humidity and a 12-hour light-dark cycle. Following a 1 week acclimatisation period the dorsal skin o...

ORGANISM(S): Mus musculus

2005-10-01 | E-MEXP-188 | biostudies-arrayexpress

ena-DATASET-CRUK-LRI-05-08-2014-14:10:54:243-46 - samples

Van Hippel-Lindau syndrome multi-region exome sequencing of two patients

EGAD00001000973 | EGA

Comparative genomic hybridization of 61 strains of proteolytic Clostridium botulinum or Clostridium sporogenes

Genomic DNA of 61 strains of proteolytic Clostridium botulinum or Clostridium sporogenes was subjected to analysis by DNA microarray.

ORGANISM(S): Clostridium botulinum

2008-12-31 | E-MEXP-1637 | biostudies-arrayexpress

Glycolysis/gluconeogenesis specialization in microbes is driven by biochemical constraints of flux sensing

Central carbon metabolism is highly conserved across microbial species, but can catalyze very different pathways depending on the organism and their ecological niche. Here, we study the dynamic reorganization of central metabolism after switches between the two major opposing pathway configurations ...

2022-01-11 | MTBLS3887 | MetaboLights

Integrated multi-omics of feces, plasm aand urine can describe and differentiate pediatric active Crohn’s Disease from remission

Background

This study aimed to obtain a holistic view of remission in pediatric Crohn’s Disease (CD) by integrating six omics datasets from three anatomical compartments.

Methods

Patients with fecal calprotectin below 250 mg/kg were c...

2025-07-09 | MTBLS9877 | MetaboLights

High resolution array-CGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer

An oligo array based high-resolution analysis of copy number alterations in 171 primary breast tumors of relatively small size and low NPI, and 49 breast cancer cell-lines. Objectives of the study were to study the molecular taxonomy and the genomic aberration patterns in a breast cancer cohort repr...

ORGANISM(S): Homo sapiens

2007-08-16 | E-GEOD-8757 | biostudies-arrayexpress

Chang - Frankia sp. CcI3 - Nitrogen limitation

Effect of nitrogen limitation on the gene expression of Frankia sp. CcI3

ORGANISM(S): Frankia sp. Ccl3

2013-10-03 | E-MEXP-3620 | biostudies-arrayexpress

Transcription profiling of human dendritic cells matured by cadherin reveals disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturation

The maturation of dendritic cells (DCs) after exposure to microbial products or inflammatory mediators plays a critical role in initiating the immune response. We found that maturation can also occur under steady state conditions, triggered by alterations in E-cadherin-mediated DC-DC adhesion. Sele...

ORGANISM(S): Homo sapiens

2008-06-16 | E-GEOD-9241 | biostudies-arrayexpress

Glucosylated hydroxymethyluracil (DNA base J) prevents transcriptional read-through in Leishmania

Some T's in nuclear DNA of trypanosomes and Leishmania are hydroxylated and glucosylated to yield base J (?-D-glucosyl-hydroxymethyluracil). In Leishmania about 99% of J is located in telomeric repeats. We show here that most of the remaining J is located at chromosome-internal RNA Polymerase II ter...

ORGANISM(S): Leishmania major

2011-10-15 | E-GEOD-32976 | biostudies-arrayexpress

Comparative genomic hybridization of Clostridium sporogenes and Clostridium botulinum strains

Clostridium botulinum is a heterogeneous Gram-positive species that comprises four genetically and physiologically distinct groups of bacteria that share the ability to produce botulinum neurotoxin, the most poisonous toxin known to man, and the causative agent of botulism, a severe disease of human...