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ProteomicsMass spectrometry-driven discovery of neuropeptides mediating nictation behavior of nematodes
Very little is known about the genetic modulation of nictation, a host-finding strategy used by infective juveniles of many pathogenic nematodes, as well as a phoretic strategy of Caenorhabditis elegans dauers. We here use a mass spectrometry-driven approach to find neuropeptides involved in the mod...
ORGANISM(S): Steinernema carpocapsae 
2022-12-08 | PXD034629 | Pride
Nictation Data-dependent acquisition Steinernema carpocapsae Peptidomics Parallel reaction monitoring Caenorhabditis elegans 
ProteomicsGlobal analysis of neuropeptides in cestodes identifies Attachin, a SIFamide homolog, as a stimulant of parasite motility and attachment
Many anthelmintics target the neuromuscular system, in particular by interfering with signalling mediated by classical neurotransmitters. Although peptidergic signalling has been proposed as a target of novel anthelmintics, current knowledge of the neuropeptide complement of many helminths is still ...
ORGANISM(S): Hymenolepis microstoma 
2022-06-13 | PXD033611 | Pride
Peptidomics Sucker Motility Peptidergic Sifamide Tapeworm 
ProteomicsMass spectrometric evidence for neuropeptide-amidating enzymes in C. elegans
Neuropeptides constitute a vast and functionally diverse family of neurochemical signaling molecules, and are widely involved in the regulation of various physiological processes. The nematode C. elegans is well-suited for the study of neuropeptide biochemistry and function, as neuropeptide biosynth...
ORGANISM(S): Caenorhabditis elegans 
2018-03-12 | PXD008942 | Pride
Peptidomics  mass spectrometry  neuropeptide  amidation  copper monooxygenase  phm  pal  pam  caenorhabditis elegans  lc-orbitrap ms 
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