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ProteomicsAPMS analysis of endogenous mGlu2 receptor interactome in mice prefrontal cortex
Metabotropic glutamate receptor 2 (mGlu2) attracts particular attention as a possible target for a new class of antipsychotics. However, the signaling pathways transducing the effects of mGlu2 in the brain remain poorly characterized. Here, we addressed this issue by identifying native mGlu2 interac...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-29 | PXD038192 | Pride
Mice apms lcmsms 
ProteomicsSILAC APMS anlysis of TSSC4 interactome
U5 snRNP is a complex particle essential for RNA splicing. U5 snRNPs undergo an intricate biogenesis that ensures that only a fully mature particle assembles into a splicing competent U4/U6•U5 tri-snRNP and enters the splicing reaction. During splicing, U5 snRNP is substantially rearranged and leave...
ORGANISM(S): Homo sapiens (Human) 
2021-06-11 | PXD024929 | Pride
Apms  silac  immunoprecipitation 
ProteomicsMS analysis of GAR1 methylation immunopurified from HEK-293 Cells
The conserved box H/ACA RNPs consist of one box H/ACA RNA and 4 core proteins: Dyskerin, NHP2, NOP10 and GAR1. The assembly of the H/ACA RNPs is a stepwise process which requires several assembly factors: SHQ1, NAF1, the Survival of Motor Neuron complex SMN, and the R2TP complex. It implicates the c...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD026752 | Pride
Methylation Apms 
ProteomicsSILAC APMS analysis of NAF1 interactome in HEK-293 cells
The conserved box H/ACA RNPs consist of one box H/ACA RNA and 4 core proteins: Dyskerin, NHP2, NOP10 and GAR1. The assembly of the H/ACA RNPs is a stepwise process which requires several assembly factors: SHQ1, NAF1, the Survival of Motor Neuron complex SMN, and the R2TP complex. It implicates the c...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD026747 | Pride
Apms Silac Interactome 
ProteomicsSILAC APMS analysis of NHP2 / Gar1 interactome in HEK-293 cells
The conserved box H/ACA RNPs consist of one box H/ACA RNA and 4 core proteins: Dyskerin, NHP2, NOP10 and GAR1. The assembly of the H/ACA RNPs is a stepwise process which requires several assembly factors: SHQ1, NAF1, the Survival of Motor Neuron complex SMN, and the R2TP complex. It implicates the c...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD026749 | Pride
Apms Interactome Silac 
ProteomicsSILAC APMS analysis of SHQ1 interactome in HEK-293 cells
The conserved box H/ACA RNPs consist of one box H/ACA RNA and 4 core proteins: Dyskerin, NHP2, NOP10 and GAR1. The assembly of the H/ACA RNPs is a stepwise process which requires several assembly factors: SHQ1, NAF1, the Survival of Motor Neuron complex SMN, and the R2TP complex. It implicates the c...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD035330 | Pride
Silac Apms 
ProteomicsSILAC APMS analysis of Pih1D3 interactome
To get insights into the function of Pih1D3 protein, we characterized its partners by performing a proteomic analysis in human cells. We fused this domain to GFP and stably expressed it in HeLa cells using site-specific integration with the Flp-In system. Following differential labeling of GFP-Pih1D...
ORGANISM(S): Homo sapiens (Human) 
2018-06-10 | PXD009499 | Pride
Human Ltq-orbitrap Hela cells Apms Silac 
ProteomicsSILAC APMS analysis of RPAP3 C-term interactome
To get insights into the function of RPAP3, we characterized its partners by performing a proteomic analysis in human cells. We fused the Cterm part of RPAP3 domain to GFP and stably expressed it in HeLa cells using site-specific integration with the Flp-In system. Following differential labeling of...
ORGANISM(S): Homo sapiens (Human) 
2018-06-10 | PXD009518 | Pride
Human Ltq-orbitrap Hela cells Apms Silac 
ProteomicsSILAC APMS analysis of Pih1D2 interactome
To get insights into the function of Pih1D2 protein, we characterized its partners by performing a proteomic analysis in human cells. We fused this domain to GFP and stably expressed it in HeLa cells using site-specific integration with the Flp-In system. Following differential labeling of GFP-Pih1D...
ORGANISM(S): Homo sapiens (Human) 
2018-06-10 | PXD009520 | Pride
Human Ltq-orbitrap Hela cells Apms Silac 
ProteomicsSILAC APMS analysis of DNAAF2 interactome
To get insights into the function of DNAAF2 protein, we characterized its partners by performing a proteomic analysis in human cells. We fused this domain to GFP and stably expressed it in HeLa cells using site-specific integration with the Flp-In system. Following differential labeling of GFP- DNAA...
ORGANISM(S): Homo sapiens (Human) 
2018-06-10 | PXD009501 | Pride
Human Ltq-orbitrap Hela cells Apms Silac 
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