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ProteomicsVariant Surface Glycoprotein expression in the Trypanosoma vivax genome C4PR_LIV
Trypanosoma vivax causes animal trypanosomiasis across Africa and South America. An accurate genome sequence is essential to functional genetics and the design of novel diagnostics, drugs and vaccines. Our aim is to improve the existing T. vivax Y486 reference genome assembly to understand the basis...
ORGANISM(S): Trypanosoma vivax (strain Y486) 
2026-10-15 | PXD075690 | Pride
Variant surface glycoprotein 
GenomicsMeasurement of variant surface glycoprotein mRNA using RNAseq
Measurement of variant surface glycoprotein mRNA using RNAseq
PRJEB38469 | ENA
TranscriptomicsP. falciparum Complicated Malaria: Modulation and Connectivity between Exportome and Variant Surface Gene Families
In temperate and sub-tropical regions of Latin America, complicated malaria manifested as hepatic dysfunction or renal dysfunction is seen in all age groups. There has been a concerted focus on understanding the patho-physiological and molecular basis of complicated malaria in children, much less is...
ORGANISM(S): Plasmodium falciparum 
2015-07-07 | E-GEOD-59844 | biostudies-arrayexpress
ProteomicsTbSAP is a novel chromatin protein repressing metacyclic Variant Surface Glycoprotein expression sites in bloodstream form Trypanosoma brucei
The African trypanosome Trypanosoma brucei is a unicellular eukaryote, which relies on a protective Variant Surface Glycoprotein (VSG) coat for survival in the mammalian host. A single trypanosome has >2000 VSG genes and pseudogenes of which only one is expressed from one of ~15 telomeric bloodstre...
ORGANISM(S): Trypanosoma brucei 
2020-11-06 | PXD022397 | Pride
Lc/ms-ms 
GenomicsTrypanosoma congolense Variant Surface Glycoprotein gene expression occurs in the absence of monoallelic transcription control
Trypanosoma congolense Variant Surface Glycoprotein gene expression occurs in the absence of monoallelic transcription control
PRJNA1505024 | ENA
UnknownGlycotyping of Trypanosoma brucei variant surface glycoprotein MITat1.8.
Not available
S-EPMC2935967 | biostudies-literature
ProteomicsThe trypanosome Variant Surface Glycoprotein mRNA is stabilized by an essential unconventional RNA-binding protein
Salivarian trypanosomes cause human sleeping sickness and economically important livestock diseases, transmitted by Tsetse flies and replicating extracellularly throughout the life cycle. The surface of "bloodstream forms", which live within mammals, is coated by a monolayer of a Variant Surface Gly...
ORGANISM(S): Trypanosoma brucei 
2021-04-14 | PXD021772 | Pride
Bloodstream forms Vsg Trypanosomes 
GenomicsTbSAP is a novel chromatin protein repressing metacyclic Variant Surface Glycoprotein expression sites in bloodstream form Trypanosoma brucei
TbSAP is a novel chromatin protein repressing metacyclic Variant Surface Glycoprotein expression sites in bloodstream form Trypanosoma brucei
PRJNA674063 | ENA
ProteomicsControl of variant surface glycoprotein expression by CFB2 in African trypanosomes and quantitative proteomic connections to translation and cytokinesis initiation
Variant Surface Glycoproteins (VSG) coat parasitic African trypanosomes and underpin antigenic variation and immune evasion. This VSG is a super-abundant virulence factor that is subject to post-transcriptional gene expression controls mediated via the VSG 3’-untranslated region (3’-UTR). To identif...
ORGANISM(S): Trypanosoma brucei 
2022-02-01 | PXD031351 | Pride
Mrna-binding  pbp1 Trypanosoma brucei  mkt1 Proteomics  rnai. 
TranscriptomicsTrypanosoma congolense Variant Surface Glycoprotein gene expression occurs in the absence of monoallelic transcription control
Antigenic variation is a very widespread process for pathogen evasion of mammalian adaptive immunity, involving the continuous change of exposed antigens. In many single-celled pathogens, antigen expression during antigenic variation is monoallelic: just a single gene from a large family is expresse...
ORGANISM(S): Trypanosoma congolense 
2026-07-31 | GSE342023 | GEO
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