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ProteomicsQuantitative Proteome Analysis Reveals Increased Content of Basement Membrane Proteins in Arteries from Patients with Type 2 Diabetes and Lower Levels among Metformin Users
We analyzed non-atherosclerotic repair arteries gathered at coronary by-pass operations from 30 patients with type 2 diabetes, as well as from 30 age- and gender-matched non-diabetic individuals. Quantitative proteome analysis was done by iTRAQ-labelling and LC-MS/MS analysis on individual arterial ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080848 | MassIVE
ProteomicsBasement Membranes from Human Retinal Blood Vessels, Inner Limiting Membranes, and Lens Capsules
Three types of BMs from adult human eyes, the inner limiting membrane, the retinal vascular BMs and the lens capsule, were isolated for analysis by 1D-SDS-PAGE and LC-MS/MS.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-29 | MSV000081772 | MassIVE
TranscriptomicsAngiogenesis gene expression upon Notch activation in human vascular smooth muscle cells
VSMCs were cultured on Jag1 or IgG-coated plates as described above. RNA was extracted using RNA isolation kit (Qiagen). Reverse-transcription PCR was done with RNA-to-cDNA kit (Applied Biosystems). cDNA was run on a TaqMan Low-Density Array, human angiogenesis panel (Applied Biosystems , Cat#437872...
ORGANISM(S): Homo sapiens 
2011-12-01 | E-GEOD-34024 | biostudies-arrayexpress
TranscriptomicsRNA expression data from glomeruli lacking von Hippel-Lindau protein in podocytes
We and others have previously shown that glomerular endothelial cells and podocytes express hypoxia-inducible transcription factors (HIFs). HIFs bind to hypoxia response elements in target genes, such as vascular endothelial growth factor, which is continually produced by podocytes throughout life....
ORGANISM(S): Mus musculus 
2010-08-03 | E-GEOD-20235 | biostudies-arrayexpress
OtherA proteomic view of basement membranes from human retinal blood vessels, inner limiting membranes, and lens capsules.
Data from ProteomeXchange, PXD ID: PXD001025. Experiment: ILM, file: ILM-2.mzml. Published as part of J Proteome Res. 2014 Jul 2 . From the Abstract: {{i}} Basement membranes (BMs) are extracellular matrix sheets comprising the laminins, type IV collagens, nidogens, and the heparan sulfate proteogl...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32310002171 | GPMDB
Resource Reanalysis 
GenomicsVascular Basement Membrane Laminins Modulate Functional Zonation of Cerebral Microvessels [scRNA-seq]
Vascular Basement Membrane Laminins Modulate Functional Zonation of Cerebral Microvessels [scRNA-seq]
PRJNA1332648 | ENA
GenomicsVascular Basement Membrane Laminins Modulate Functional Zonation of Cerebral Microvessels [RNA-seq]
Vascular Basement Membrane Laminins Modulate Functional Zonation of Cerebral Microvessels [RNA-seq]
PRJNA1334288 | ENA
GenomicsVascular Basement Membrane Laminins Modulate Functional Zonation of Cerebral Microvessels
Vascular Basement Membrane Laminins Modulate Functional Zonation of Cerebral Microvessels
PRJNA1335210 | ENA
ProteomicsFlow-induced reorganization of laminin-integrin networks within the endothelial basement membrane uncovered by proteomics
Objective The vessel wall is continuously exposed to hemodynamic forces generated by blood flow. Endothelial mechanosensors perceive and translate mechanical signals via cellular signaling pathways into biological processes that control endothelial development, phenotype and function. Here, we aim t...
ORGANISM(S): Homo sapiens (Human) 
2020-04-29 | PXD014526 | Pride
Shear stress Proteomics Inflammation Basement membrane Flow Laminin Integrin Endothelium Extracellular matrix Tnfα 
ProteomicsBasement Membranes from Human Retinal Blood Vessels, Inner Limiting Membranes, and Lens Capsules
Three types of BMs from adult human eyes, the inner limiting membrane, the retinal vascular BMs and the lens capsule, were isolated for analysis by 1D-SDS-PAGE and LC-MS/MS.
ORGANISM(S): Homo sapiens (Human) 
2014-07-16 | PXD001025 | Pride
Proteomics Collagens Mass spectrometry Nidogens Perlecan Laminin Collagen iv Basement membrane 
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