Vascular biology/endothelial cells

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Unknown (388)
Transcriptomics (189)
Genomics (125)
Proteomics (17)
Models (6)
Other (6)
Metabolomics (5)
Methylation profiling (1)

Organisms

Homo sapiens (155)
Mus musculus (57)
Acidithiobacillus ferrooxidans ATCC 53993 (11)
Aerococcus urinae NBRC 15544 = CCUG 36881 (11)
Allexis (11)
Arabidopsis thaliana (11)
Cyanophora paradoxa (11)
Ensifer adhaerens (11)
Enterococcus faecalis (11)
Globicatella sanguinis (11)
Helianthus annuus (11)
Histomonas meleagridis (11)
Leishmania major strain Friedlin (11)
Listeria monocytogenes (11)
Lotus japonicus (11)
Marchantia polymorpha (11)
Medicago truncatula (11)
Methylohalobius crimeensis 10Ki (11)
Mus musculus (11)
Mycobacterium tuberculosis (11)
Ophrys garganica (11)
Ophrys sphegodes (11)
Oryza sativa Indica Group (11)
Sus scrofa (3)
Danio rerio (3)
Streptococcus suis 05ZYH33 (2)
Gallus gallus (2)
Bos taurus (1)
Macaca fascicularis (1)
Rattus norvegicus (1)

Organisms

Homo sapiens (66)
Mus musculus (23)
Danio rerio (2)
Macaca fascicularis (1)
Canis lupus familiaris (1)
Sus scrofa (1)
Rattus norvegicus (1)

Repository

biostudies-arrayexpress (129)
ENA (108)
geo (82)
pride (11)
BioModels (6)
MetaboLights (5)
iProX (3)
MassIVE (3)
EGA (2)

Tissue

Cell culture (3)
Heart (2)
Liver (2)
Aortic endothelial cell (1)
Aortic smooth muscle cell (1)
Blood plasma (1)
Cardiac muscle cell (1)
Endothelial cell (1)
Endothelial cell of umbilical vein (1)
Endothelial cell of vascular tree (1)
Heart endothelium (1)
Pericyte cell (1)

Disease

Neuroendocrine tumor (1)
AIDS-KS, HIV+, nodular (late) stage (1)
Glioblastoma (1)
Invasive ductal carcinoma (1)
Cardiomyopathy (1)
Cardiovascular system disease (1)
Chronic fatigue syndrome (1)

Technology Type

Mass Spectrometry (11)
Shotgun proteomics (7)
Mass spectrometry (4)
Top-down proteomics (2)
Mass spectrometry assay (1)
Affinity purification coupled with mass spectrometry proteomics (1)
Data-independent acquisition (1)
SWATH MS (1)

Instrument Platform

Illumina HiSeq 2500 (4)
Qiagen-Qiacube (2)
Affymetrix GeneChip Scanner 3000 7G (2)
NextSeq 2000 (2)
Illumina HiSeq 4000 (2)
NextSeq 500 (2)
Q Exactive (2)
Liquid Chromatography MS - alternating - reverse phase (2)
Agilent Microarray Hybridization Chamber Kit and Hybridization oven rotator (1)
Do not apply (1)
Illumina MiSeq (1)
Illumina NovaSeq 6000 (1)
TimsTOF Pro (1)
Liquid Chromatography MS - alternating - HILIC (1)
Gas Chromatography MS - positive (1)
Liquid Chromatography MS - positive - reverse phase (1)
Liquid Chromatography MS - negative - reverse phase (1)

Publication Date

2014 (34)
2010 (21)
2024 (20)
2025 (18)
2023 (15)
2015 (15)
2011 (14)
2012 (13)
2008 (12)
2021 (11)
2026 (9)
2009 (9)
2013 (8)
2020 (7)
2019 (6)
2022 (5)
2017 (5)
2007 (5)
2018 (4)
2006 (4)
2016 (2)
2005 (1)
2004 (1)

UNIPROT ID/AC

Q03135 (3)
P31749 (3)
P08238 (2)
Q9Y5W3 (2)
Q15119 (2)
O14733 (2)
P01112 (2)
Q05397 (2)
P62158 (2)
O15530 (2)
Q13233 (2)
Q07889 (2)
P29353 (2)
P60484 (2)
P45983 (2)
P12931 (2)
P62993 (2)

ENSEMBL ID

ENST00000297494 (1)

CHEBI ID

CHEBI:29108 (3)
CHEBI:203600 (2)
CHEBI:57600 (2)
CHEBI:18348 (2)
CHEBI:16480 (2)
CHEBI:17552 (2)
CHEBI:16467 (1)
CHEBI:17084 (1)

Metabolite Name

Adefovir Dipivoxil (Preveon, Hepsera) (1)
Indomethacin (Indocid, Indocin) (1)
MLS001148580-01!6ALPHA,9ALPHA-DIFLUOROPREDNISOLONE 21-ACETATE 17-BUTYRATE (1)
Toremifene Citrate (Fareston, Acapodene) (1)
[(1S,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate (1)
(+)-Cycloolivil 4'-O-¦Â-D-glucopyranoside (1)
(+)-Lyoniresinol 2¦Á-O-¦Â-D-glucopyranoside (1)
(-)-Medicocarpin;Medicarpin 3-O-glucoside (1)
(-)-Syringaresinol-4-O-¦Â-D-glucopyranoside (1)
(-)-threo-Iso(homo)2-citrate;(-)-threo-1-Hydroxy-1,2,5-pentanetricarboxylic acid;1-Hydroxypentane-1,2,5-tricarboxylate;threo-(Homo)2-isocitrate (1)
(1)Benzopyrano(5,4,3-cde)(1,3)dioxolo(4,5-h)(1)benzopyran-5,11-dione, 1,2,3-trimethoxy- (1)
(1,3-Dihydroxy-6,8a-dimethyl-3-propan-2-yl-1,2,3a,4,5,8-hexahydroazulen-4-yl) 3,4-dimethoxybenzoate (1)
(10-Hydroxy-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-f]chromen-9-yl) (Z)-2-methylbut-2-enoate (1)
(11E)-11-Octadecenoic acid (1R,2S)-2-[[(Z)-9-hexadecenoyl]oxy]-1-methylpropyl ester (1)
(13S)-13-Ethoxy-1,2-dimethoxy-12-methyl-13H-[1,3]benzodioxolo[5,6-c]phenanthridine (1)
(14E)-11-hydroxy-14-(1H-imidazol-5-ylmethylidene)-2-methoxy-9-(2-methylbut-3-en-2-yl)-2,13,16-triazatetracyclo[7.7.0.01,13.03,8]hexadeca-3,5,7-triene-12,15-dione (1)
(14S)-9,20,21,25-Tetramethoxy-15-methyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-1(30),3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,28,31-tetradecaen-2-one (1)
(19E,21E,23E,25E,27E,29E,31E)-17-[7-(4-aminophenyl)-5-hydroxy-4-methyl-7-oxoheptan-2-yl]-1,3,5,33,37-pentahydroxy-18,36-dimethyl-16,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-9,13,15-trione (1)
(19E,21E,23E,25E,27E,29E,31E)-17-[7-(4-aminophenyl)-5-hydroxy-4-methyl-7-oxoheptan-2-yl]-1,3,5,7,33,37-hexahydroxy-18-methyl-9,13,15-trioxo-16,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate (1)
(1E)-4-hydroxy-1-(4-hydroxy-3-methoxyphenyl)dodec-1-en-3-one (1)
(1E,3Z)-buta-1,3-diene-1,2,4-tricarboxylate (1)
(1R)-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium-7-ol (1)
(1R)-1-[[(2S,3R,11bS)-3-ethyl-9,10-dimethoxy-1,2,3,4,5,6,7,11b-octahydrobenzo[a]quinolizin-5-ium-2-yl]methyl]-7-methoxy-1,2,3,4-tetrahydroisoquinolin-2-ium-6-ol (1)
(1R,10R)-5-amino-14-oxido-14-oxo-13,15,18-trioxa-2,4,6,9-tetraza-14lambda5-phosphatetracyclo[8.8.0.03,8.012,17]octadeca-3(8),4-diene-7,11-dione (1)
(1R,14R,24S)-24-Methoxy-5,7,19,21,25-pentaoxa-13-azahexacyclo[12.11.0.02,10.04,8.015,23.018,22]pentacosa-2,4(8),9,15(23),16,18(22)-hexaene (1)
(1R,2'S,3'aS,12S,14S)-2',12-dimethylspiro[13-oxa-2,10,17-triazatetracyclo[10.3.2.02,11.04,9]heptadeca-4,6,8,10-tetraene-14,4'-3,3a-dihydro-2H-imidazo[1,2-a]indole]-1',3,16-trione (1)
(1R,2R,5R,8R,9S,10R,11S)-11-methyl-6-methylidene-16-oxo-15-oxapentacyclo[9.3.2.15,8.01,10.02,8]heptadecane-9-carboxylate (1)
(1R,2R,5S,8S,9S,10R,11R,12R,13S)-5,12,13-trihydroxy-11-methyl-6-methylidene-16-oxo-15-oxapentacyclo[9.3.2.15,8.01,10.02,8]heptadecane-9-carboxylate (1)
(1R,2R,6R,11S,13S,14R,21R)-7,19,23-Triazahexacyclo[9.9.1.11,13.12,6.07,21.014,19]tricosane (1)
(1R,2S,13S,16S,25S,27S)-1,2,24,24-tetramethyl-22-(2-methylprop-1-enyl)-18,21,23,26-tetraoxa-4-azaoctacyclo[14.13.0.02,13.03,11.05,10.017,19.017,27.020,25]nonacosa-3(11),5,7,9-tetraen-16-ol (1)

First Public Date

2014 (27)
2025 (16)
2026 (15)
2024 (14)
2023 (13)
2021 (7)
2020 (6)
2022 (3)
2019 (2)
2017 (2)
2015 (2)
2018 (1)

Modelling Approach

Ordinary differential equation model (6)

Lab affiliation

Centre for Genomic Regulation (CRG) (1)
Department of Anesthesiology & Perioperative Medicine, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA (1)
Department of Molecular Hematology, Sanquin Research, Amsterdam 1066CX, the Netherlands (1)
Dept. Oncology Pathology, Karolinska Institutet, and Scilifelab, Stockholm, Sweden (1)
Division of Vascular Oncology and Metastasis Research, German Cancer Research Center (DKFZ), Heidelberg, Germany. European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. (1)
Division of Vascular Oncology and Metastasis Research,German Cancer Research Center (DKFZ), Heidelberg, Germany. European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. (1)
Faculty of Medicine, Health and Human Sciences, MacquarieUniversity. (1)
Max Planck Institut for Molecular Biomedicine Bioanalytical Mass Spectromentry Röntgenstr. 20 48149 Münster, Germany (1)
Max Planck Institut or Molecular Biomedicine Bioanyltical Mass Spectrometry Röntgenstr. 20 48149 Münster Germany (1)
Unit of functional proteomic, metabolomi and network analysis, Centro Cardiologico Monzino IRCCS, Milan, Italy (1)
Washington University in St. Louis - School of Medicine Division of Endocrinology, Metabolism & Lipid Research (1)

IsPrivate

False (6)

Modification

4-tetrahydrothiazine-3-carboxylic acid (1)

Study type

Transcription profiling by array (86)
RNA-seq of coding RNA (12)
ChIP-seq (5)
Other (4)
Unknown experiment type (3)
RNA-seq of coding RNA from single cells (3)
Cell line - High-throughput sequencing (2)
Transcription profiling by RT-PCR (2)
Comparative genomic hybridization by array (2)
Methylation profiling by high throughput sequencing (2)
ChIP-chip by tiling array (1)
Human - High-throughput sequencing (1)
Animal - High-throughput sequencing (1)
CLIP-seq (1)
DNA-seq (1)
Methylation profiling by array (1)
CUT&RUN (1)
RNA-seq of non coding RNA (1)

Release Date

2021 (48)
2014 (42)
2025 (33)
2015 (33)
2022 (32)
2024 (30)
2013 (27)
2012 (27)
2023 (26)
2020 (26)
2018 (25)
2010 (25)
2019 (24)
2011 (23)
2017 (20)
2016 (18)
2009 (18)
2008 (15)
2026 (6)
2006 (6)
2007 (4)
2004 (4)
2005 (2)
2002 (2)
2003 (1)

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Differential endothelial cell gene expression by African Americans versus Caucasian Americans: A possible contribution to health disparity in vascular disease and cancer

Background: African Americans (AA) have increased burdens of cardiovascular disease and cancer compared to Caucasian Americans (CA). This study addresses the possibility that genetic differences affecting the biology of the vascular endothelium could be a factor contributing to this health disparity...

ORGANISM(S): Homo sapiens

2010-07-02 | E-GEOD-22688 | biostudies-arrayexpress

Genetic Framework for GATA Factor Function in Vascular Biology

Vascular endothelial dysfunction underlies the genesis and progression of numerous diseases. Whereas the GATA transcription factor GATA-2 is expressed in endothelial cells and is implicated in coronary heart disease, it has been studied predominantly as a master regulator of hematopoiesis. As many q...

ORGANISM(S): Homo sapiens

2011-08-11 | E-GEOD-29531 | biostudies-arrayexpress

Differentially regulated splice variants and systems biology analysis of Kaposi's Sarcoma-associated Herpesvirus-infected lymphatic endothelial cells

Alternative RNA splicing greatly increases proteome diversity, and the possibility of studying genome-wide alternative splicing (AS) events becomes available with the advent of high-throughput genomics tools devoted to this issue. Kaposi’s sarcoma associated herpesvirus (KSHV) is the etiological age...

ORGANISM(S): Homo sapiens

2011-05-05 | E-GEOD-26341 | biostudies-arrayexpress

Vascular properties of breast cancer intrinsic subtypes

Interactions of cancer cells with the vasculature are essential for tumor growth and likely promote metastatic progression. Endothelial cell content and lympho-vascular invasion are generally associated with tumor aggressiveness, however, these features are generally not employed in the clinic. We a...

ORGANISM(S): Homo sapiens

2014-01-01 | E-GEOD-37145 | biostudies-arrayexpress

Physiological Vascular Permeability Requires Induction of Endothelial NR4A1 by Progesterone Receptor [RNA-Seq]

Vascular permeability is frequently associated with inflammation and it is triggered by chemokines and by a cohort of secreted permeability factors, such as VEGF. In contrast, here we showed that the physiological vascular permeability that precedes implantation is directly controlled by progestero...

ORGANISM(S): Homo sapiens

2014-01-01 | E-GEOD-43788 | biostudies-arrayexpress

Comparison of human embroynic stem cell derived vascular cells to mature human vascular and hematopoietic cells

The pathways involved in hierarchical differentiation of human embryonic stem cells (hESC) into abundant and durable endothelial cells (EC) are unknown. We employed an EC-specific VE-cadherin promoter driving GFP (hVPr-GFP) to screen for factors that augmented yields of vascular-committed ECs from h...

ORGANISM(S): Homo sapiens

2010-01-05 | E-GEOD-19735 | biostudies-arrayexpress

An RNA-Seq transcriptome and splicing database of neurons, glia, and vascular cells of the cerebral cortex

Purpose: To better understand the function of the various cell types of the brain, we prospectively purified neurons, astrocytes, oligodendrocyte precursor cells, newly formed oligodendrocytes, myelinating oligodendrocytes, microglia, endothelial cells, and pericytes from mouse cerebral cortex. We g...

ORGANISM(S): Mus musculus

2014-08-15 | E-GEOD-52564 | biostudies-arrayexpress

Vascular histone deacetylation by pharmacological HDAC inhibition [SAHA, RNA-seq]

HDAC inhibitors are thought to regulate gene expression by post-translational modification of histone as well as non-histone proteins. Often studied at single loci, increased histone acetylation is the paradigmatic mechanism of action, however, little is known of the extent of genome-wide changes of...

ORGANISM(S): Homo sapiens

2014-02-23 | E-GEOD-54912 | biostudies-arrayexpress

Vascular histone deacetylation by pharmacological HDAC inhibition [TSA, RNA-seq]

ORGANISM(S): Homo sapiens

2014-02-23 | E-GEOD-37376 | biostudies-arrayexpress

Non-coding small RNA profiling by high throughput sequencing of bovine primary retinal microvascular endothelial cells

The aim of this study was to identify and quantify microRNAs and other small regulatory RNAs expressed in primary retinal microvascular endothelial cells (RMECs) using deep sequencing. RMECs were isolated, RNA extracted, a small RNA library prepared and deep sequencing performed. A total of 6.8 mill...

ORGANISM(S): Bos taurus

2012-02-13 | E-GEOD-31340 | biostudies-arrayexpress

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