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TranscriptomicsHigh-throughput sequencing of endogenous small RNAs from rat vascular smooth muscle cells with and without Angiotensin II stimulation
Angiotensin II (Ang II)-mediated vascular smooth muscle cells (VSMC) dysfunction plays a critical role in cardiovascular diseases. However, the role of microRNAs (miRNAs) in this process is unclear. We used small RNA deep sequencing to profile Ang II-regulated miRNAs in rat VSMC and evaluated their ...
ORGANISM(S): Rattus norvegicus 
2012-03-23 | E-GEOD-35664 | biostudies-arrayexpress
TranscriptomicsRNA sequencing of pancreatic islets and islet-derived macrophages and endothelial cells modulated by vascular endothelial growth factor-A signaling
Pancreatic islet endocrine cell and endothelial cell (EC) interactions mediated by vascular endothelial growth factor-A (VEGF-A) signaling are important for islet endocrine cell differentiation and the formation of highly vascularized islets. To dissect how VEGF-A signaling modulates intra-islet vas...
ORGANISM(S): Mus musculus 
2015-09-01 | E-GEOD-72546 | biostudies-arrayexpress
UnknownNeoatherosclerosis development following bioresorbable vascular scaffold implantation in diabetic and non-diabetic swine.
Not available
S-EPMC5595285 | biostudies-literature
TranscriptomicsIL-4 mediated gene expression profiles in vascular endothelial cells
Endothelial cell activation and dysfunction underlie many vascular disorders, including atherosclerosis and inflammation. Here, we show that interleukin (IL)-4 markedly induced vascular cell adhesion molecule (VCAM)-1, both in cultured endothelial cells and in the intact endothelium in mice. Combine...
ORGANISM(S): Homo sapiens 
2011-05-01 | E-GEOD-28117 | biostudies-arrayexpress
UnknownCoronary magnetic resonance imaging after routine implantation of bioresorbable vascular scaffolds allows non-invasive evaluation of vascular patency.
Not available
S-EPMC5784929 | biostudies-literature
TranscriptomicsVascular histone deacetylation by pharmacological HDAC inhibition [SAHA, RNA-seq]
HDAC inhibitors are thought to regulate gene expression by post-translational modification of histone as well as non-histone proteins. Often studied at single loci, increased histone acetylation is the paradigmatic mechanism of action, however, little is known of the extent of genome-wide changes of...
ORGANISM(S): Homo sapiens 
2014-02-23 | E-GEOD-54912 | biostudies-arrayexpress
TranscriptomicsVascular histone deacetylation by pharmacological HDAC inhibition [TSA, RNA-seq]
HDAC inhibitors are thought to regulate gene expression by post-translational modification of histone as well as non-histone proteins. Often studied at single loci, increased histone acetylation is the paradigmatic mechanism of action, however, little is known of the extent of genome-wide changes of...
ORGANISM(S): Homo sapiens 
2014-02-23 | E-GEOD-37376 | biostudies-arrayexpress
GenomicsGenetic Framework for GATA Factor Function in Vascular Biology
Vascular endothelial dysfunction underlies the genesis and progression of numerous diseases. Whereas the GATA transcription factor GATA-2 is expressed in endothelial cells and is implicated in coronary heart disease, it has been studied predominantly as a master regulator of hematopoiesis. As many q...
ORGANISM(S): Homo sapiens 
2011-08-11 | E-GEOD-29531 | biostudies-arrayexpress
UnknownA real-world experience with a thin-strut bioresorbable vascular scaffold system: a single-centre study.
Not available
S-EPMC11905108 | biostudies-literature
UnknownShape memory polymer technology in peripheral vascular embolization.
Not available
S-EPMC11488294 | biostudies-literature
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