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ProteomicsSpxA1 and SpxA2 Function as a Stoichiometry-Dependent Regulatory Rheostat Governing Virulence Gene Expression in Group A Streptococcus — DIA Proteomics
Group A Streptococcus (GAS) encodes two paralogs of the Spx transcriptional regulator, SpxA1 and SpxA2, which interact with RNA polymerase to modulate virulence gene expression. SpxA2 is directly regulated by the LiaFSR three-component system in response to antimicrobial peptide stress. To define ho...
ORGANISM(S): Streptococcus pyogenes MGAS315 
2026-07-13 | PXD079489 | Pride
Spx Group a streptococcus Covr 
UnknownSoft anatomy and morphological variation in <i>Daptomys peruviensis</i> (Rodentia, Cricetidae), a rare ichthyomyine from the northwestern Amazonian forests.
Not available
S-EPMC11890035 | biostudies-literature
TranscriptomicsTranscription profiling of 91 human and mouse samples across a diverse array of tissues, organs, and cell lines to provide a preliminary, but substantial, description of the normal mammalian transcriptome.
High-throughput gene expression profiling has become an important tool for investigating transcriptional activity in a variety of biological samples. To date, the vast majority of these experiments have focused on specific biological processes and perturbations. Here, we have generated and analyzed ...
ORGANISM(S): Mus musculus 
2007-12-19 | E-GEOD-97 | biostudies-arrayexpress
UnknownThe Genetic Landscape of Ocular Adnexa MALT Lymphoma Reveals Frequent Aberrations in NFAT and MEF2B Signaling Pathways.
Not available
S-EPMC9075502 | biostudies-literature
UnknownEvidence for the Effect of Vaccination on Host-Pathogen Interactions in a Murine Model of Pulmonary Tuberculosis by Mycobacterium tuberculosis.
Not available
S-EPMC7248268 | biostudies-literature
TranscriptomicsTranscription profiling of human cell lines and tissues (Novartis/GNF)
High-throughput gene expression profiling has become an important tool for investigating transcriptional activity in a variety of biological samples. To date, the vast majority of these experiments have focused on specific biological processes and perturbations. Here, we have generated and analyzed ...
ORGANISM(S): Homo sapiens 
2002-03-19 | E-MEXP-18 | biostudies-arrayexpress
UnknownLMO2 Confers Synthetic Lethality to PARP Inhibition in DLBCL.
Not available
S-EPMC6752209 | biostudies-literature
TranscriptomicsMucosal transcriptomics implicates under expression of FAM5C in the pathogenesis of ulcerative colitis
Background and aims: Mucosal abnormalities are potentially important in the primary pathogenesis of ulcerative colitis (UC). We investigated the mucosal transcriptomic expression profiles of biopsies from patients with UC and healthy controls (HC), taken from macroscopically non-inflamed tissue fr...
ORGANISM(S): Homo sapiens 
2014-09-05 | E-GEOD-48634 | biostudies-arrayexpress
UnknownA Composition-Dependent Molecular Clutch Between T Cell Signaling Condensates and Actin
Not available
S-BIAD6 | bioimages
UnknownPredicting Mortality in Children With Pediatric Acute Respiratory Distress Syndrome: A Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology Study.
Not available
S-EPMC7237024 | biostudies-literature
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