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ProteomicsOptimization of statistical methods impact on quantitative proteomics data
As tools for quantitative label-free mass spectrometry (MS) rapidly develop a consensus about the best practices is not apparent. In the work described here we compared five popular statistical methods for detecting differential protein expression from quantitative MS data using both controlled expe...
ORGANISM(S): Candida albicans (Yeast) 
2020-01-13 | PXD002099 | Pride
Reproducibility Statistical methods Proteomics Quantitative analysis Rots Label-free mass spectrometry 
ProteomicsLiver lipid metabolism is altered by increased circulating estrogen to androgen ratio in the liver of male mouse
Estrogens are suggested to lower the risk of developing metabolic syndrome in both sexes. In this study, we investigated how the increased circulating estrogen-to-androgen ratio (E/A) alters liver lipid metabolism in males. Mice expressing human aromatase enzyme (AROM+ mice), and thus having high ci...
ORGANISM(S): Mus musculus (Mouse) 
2015-12-23 | PXD002025 | Pride
Aromatase Phospholipid Label free quantitative proteomics Metabolomics Liver Male mouse 
TranscriptomicsSpatial variation in transcript and protein abundance of Atlantic salmon during feeding migration in the Baltic Sea
In this study, transcriptomics was used to investigate Atlantic salmon (Salmo salar) sampled from three different field locations within Baltic Sea (Baltic Main Basin (CBS), Gulf of Finland (GoF) and Bothnian Sea (BS)) during marine migration. RNA labeling, hybridizations, and scanning were performe...
ORGANISM(S): Salmo salar 
2015-01-23 | E-MTAB-3041 | biostudies-arrayexpress
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