Ventral tegmental area

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Unknown (1349)
Genomics (109)
Transcriptomics (99)
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Organisms

Mus musculus (68)
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Organisms

Mus musculus (52)
Rattus norvegicus (23)
Homo sapiens (12)
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Repository

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geo (78)
biostudies-arrayexpress (29)
pride (8)
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Tissue

Ventral tegmental area (2)
Substantia nigra (2)
Pylorus (1)
Synovial membrane of synovial joint (1)
Subthalamic nucleus (1)
Body of tongue (1)
Myometrium (1)
Dorsal root ganglion (1)
Set of muscles of vertebral column (1)
Pharyngeal mucosa (1)
Vena cava (1)
Mammalian vulva (1)
Urethra (1)
Medulla of organ (1)
Fundus of stomach (1)
Deltoid (1)
Superior vestibular nucleus (1)
Substantia nigra pars compacta (1)
Pericardium (1)
Synovial joint (1)
Mucosa of oral region (1)
Mixed endometrium and ovary (1)
Umbilical vein endothelium (1)
Cerebellar vermis (1)
Cardia of stomach (1)
Inferior vagus X ganglion (1)
Adrenal cortex (1)
Peritoneum (1)
Nipple (1)
Trigeminal ganglion (1)

Disease

Parkinson's disease (2)
Adenocarcinoma (1)
Adenomyosis (1)
Uterine fibroid (1)
Neuromuscular pain (1)
Endometriosis (1)
Rheumatoid arthritis (1)
Prostate cancer (1)
Breast cancer (1)
Hepatocellular carcinoma (1)
Melanoma (1)
Benign prostatic hyperplasia (1)
Normal (1)
Cocaine addiction (1)
Breast Carcinoma (1)

Technology Type

Mass Spectrometry (8)
Shotgun proteomics (5)
Mass spectrometry assay (2)
Bottom-up proteomics (2)
Data-dependent acquisition (1)
Gel-based experiment (1)
SRM/MRM (1)

Instrument Platform

Illumina HiSeq 2500 (3)
Liquid Chromatography MS - negative - hilic (2)
Liquid Chromatography MS - positive - hilic (2)
QExactive (2)
NextSeq 500 (1)
Q Exactive (1)
LTQ Orbitrap Elite (1)
LTQ Orbitrap Velos (1)
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2012 (4)
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2014 (2)
2011 (2)
2008 (2)
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2018 (1)
2006 (1)
2003 (1)

UNIPROT ID/AC

A0A024R563 (2)
A0A024R8H9 (2)
A0A024RAN2 (2)
A0A024RC46 (2)
A0A087WT59 (2)
A0A087WTX5 (2)
A0A087WUD1 (2)
A0A087WVW2 (2)
A0A087WWA5 (2)
A0A087WWK8 (2)
A0A087WXI0 (2)
A0A087WYL9 (2)
A0A087WZE9 (2)
A0A087X130 (2)
A0A087X1V9 (2)
A0A0A0MR66 (2)
A0A0A0MS07 (2)
A0A0A0MS51 (2)
A0A0A0MSA7 (2)
A0A0C4DG89 (2)
A0A0C4DGT3 (2)
A0AVT1 (2)
A0FGR8 (2)
A0FGR8-2 (2)
A0FGR8-6 (2)
A0JLT2 (2)
A0JNW5 (2)
A0M8Q6 (2)
A0MZ66 (2)
A1A4S6 (2)

ENSEMBL ID

ENSG00000147251 (2)
ENSG00000170477 (2)
ENSG00000204131 (2)
ENSG00000229353 (2)
ENSG00000176092 (1)
ENSG00000247315 (1)

Metabolite Name

Phenol, 2-[4-[(3,5-dichlorophenyl)amino]-6-methyl-2-pyrimidinyl]- (2)
4-Amino-2-oxo-1,2-dihydropyrimidine-5-carboxylic acid (2)
Arachidonic sulfonic acid (2)
4(5H)-Thiazolone, 5-(6-quinolinylmethylene)-2-[(2-thienylmethyl)amino]-, (5Z)- (2)
7-Hydroxy-6-methoxy-3-methyl-5-(propan-2-ylidene)furo[2,3,4-de]chromen-2(5H)-one (2)
3-Methyl-1H-pyrazole-4-carbaldehyde (2)
GDP-mannose (2)
Gamma-Glutamylglutamine (2)
Adenylsuccinic acid (2)
Lys-Asp (2)
6-Benzyl-3-butan-2-yl-9-(7-hydroxy-6-oxooctyl)-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone (2)
MES (2)
LPG(18:1(9Z)) (2)
Ile-Leu (2)
Ala-Glu (2)
Valine (2)
2-Aminopurine (2)
Citrulline (2)
Pantothenol (2)
4-Hydroxyisoleucine (2)
Glucose 6-phosphate (2)
Phe-Thr (2)
Leu-Ile (2)
Phe-Val (2)
Uridine 5'-diphosphate (UDP) (2)
Isoleucine (2)
Uridine (2)
Hypoxanthine (2)
M532T131 (1)
M502T118 (1)

First Public Date

2014 (15)
2025 (14)
2021 (14)
2026 (12)
2024 (12)
2023 (8)
2020 (8)
2022 (6)
2019 (3)
2017 (3)
2015 (3)
2018 (1)
2016 (1)
2013 (1)

Study type

Transcription profiling by array (16)
RNA-seq of coding RNA (8)
Transcription profiling by SAGE (2)
Unknown experiment type (1)
ChIP-seq (1)
RNA-seq of coding RNA from single cells (1)

Release Date

2022 (133)
2025 (130)
2021 (125)
2019 (117)
2024 (107)
2017 (99)
2018 (98)
2020 (96)
2023 (96)
2016 (75)
2014 (53)
2015 (52)
2013 (40)
2012 (32)
2011 (25)
2009 (20)
2010 (19)
2008 (13)
2026 (13)
2007 (10)
2004 (7)
2005 (5)
2006 (4)
2003 (2)
2002 (2)
2001 (2)
1999 (2)
1998 (1)

Lab affiliation

Charles B. G. Murphy Professor of Psychiatry Department of Psychiatry New haven Ct USA (1)
Department of Chemistry and Biochemistry, University of Maryland, College Park (1)
Department of Pharmacology, University of Arizona College of Medicine (1)
Department of Pharmacology, University of Arizona College of Medicine - Tucson (1)
Director of Women's Health Research Women's Service Line Inova Health System (1)
MRC toxicology unit Hodgkin building Lancaster road LE1 9HN Leicester United Kingdom (1)
Proteomics Core Facility, Biozentrum, University of Basel, Switzerland (1)
Rappaport Faculty of Medicine Technion, Israel Institute of Technology, Haifa, Israel (1)

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Age-mediated transcriptomic changes in adult mouse brain ventral tegmental area

Substantia nigra pars compacta (SNpc) is highly sensitive to normal aging and selectively degenerates in Parkinson's disease. However, ventral tegmental area (VTA), a region adjacent to SNpc, is less affected in PD. Until now, molecular mechanisms behind VTA aging have not been fully investigated us...

ORGANISM(S): Mus musculus

2013-05-29 | E-GEOD-45044 | biostudies-arrayexpress

PatchSeq experiment on somatostatin-expressing (Sst) neurons from mouse ventral tegmental area (VTA). Full-length single cell sequencing.

Experiment was done as a part of multi-methodological description of Sst-neurons subtypes in mouse VTA, aiming to reveal their transcriptional profiles and neurotransmitter nature.

ORGANISM(S): Mus musculus

2020-06-02 | E-MTAB-8780 | biostudies-arrayexpress

RNA-SEQ profiling of dopaminergic neurons from the substantia nigra pars compacta and ventral tegmental area regions of the mouse mid-brain

RNA-SEQ profiling of dopaminergic neurons from the substantia nigra pars compacta and ventral tegmental area regions of the mouse mid-brain Murine midbrain dopaminergic neurons from the SNpc and VTA regions

ORGANISM(S): Mus musculus

2015-07-27 | E-GEOD-64452 | biostudies-arrayexpress

Parkinson's disease mouse brain proteome profiling

We compared the proteome from a vulnerable region (Substantia nigra pars compacta, SNc) of wild-type and Parkinsonian mice to that of an adjacent, less vulnerable, region (Ventral tegmental area, VTA) and identified several proteins which exhibited both spatiotemporal- and genotype-restricted change...

ORGANISM(S): Mus Musculus (ncbitaxon:10090)

2016-12-25 | MSV000080437 | MassIVE

: The effects of chronic morphine on the endogenous cannabinoid system in the ventral tegmental area

The United States is currently facing a severe opioid epidemic, therefore addressing how opioids induce rewarding behaviors could be key to a solution for this medical and societal crisis. Recently, the endogenous cannabinoid system has emerged as a hot topic in the study of opioid reward but relati...

ORGANISM(S): Rattus norvegicus (Rat)

2021-04-08 | PXD023096 | Pride

Transcription profiling of dopaminergic neurons of the substantia nigra pars compacta (SNc) and the ventral tegmental area from normal rats

The cardinal clinical features of Parkinson's disease result from selective loss of midbrain dopaminergic neurons. The goal of this experiment is to determine the gene expression profiles of these neurons by studying untreated rat substantia nigra pars compacta (SNc) and ventral tegmental area (VTA...

ORGANISM(S): Rattus norvegicus

2007-10-27 | E-GEOD-1157 | biostudies-arrayexpress

Changes in Gene Expression within the Ventral Tegmental Area Following Loss-of-Control Alcohol Drinking by Alcohol-Preferring (P) Rats

The objective of this study was to determine changes in gene expression in the ventral tegmental area (VTA) following loss-of-control alcohol drinking by alcohol-preferring (P) rats. Adult female P rats (n = 7) were given concurrent access to 10, 20 and 30% EtOH for four 1-hr sessions daily for 10 w...

ORGANISM(S): Rattus norvegicus

2013-06-01 | E-GEOD-42578 | biostudies-arrayexpress

Comparison of Differences in Gene Expression in the Ventral Tegmental Area of 5 Pairs of Rat Lines Selectively Bred for High or Low Alcohol Consumption

The objective of this study was to determine common innate differences in gene expression in the ventral tegmental area (VTA) among the selectively bred (a) alcohol-preferring (P) vs. alcohol-non-preferring (NP) rats: (b) high-alcohol-drinking (HAD) vs. low-alcohol-drinking (LAD) rats (both replicat...

ORGANISM(S): Rattus norvegicus

2012-07-31 | E-GEOD-31695 | biostudies-arrayexpress

The effect of early life social stress on mouse Ventral Tegmental Area transcriptomic profile

PRJNA818634 | ENA

Comparison of gene expression profile in embryonic mesencephalon and neuronal primary cultures

In the mammalian central nervous system (CNS) an important contingent of dopaminergic neurons are localized in the substantia nigra and in the ventral tegmental area of the ventral midbrain. They constitute an anatomically and functionally heterogeneous group of cells involved in a variety of regula...

ORGANISM(S): Rattus norvegicus

2009-05-10 | E-GEOD-15920 | biostudies-arrayexpress

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