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TranscriptomicsGene expression in colon cancer stem cells (CSC) cultures identified by Wnt signaling levels
Primary colon CSC cultures were transduced with a Wnt responsive construct (TOP-GFP) and were single cell cloned. 10% highest and lowest TOP-GFP cell fractions were FACS sorted and arrayed. Primary colon CSC cultures with a responsive construct (TOP-GFP): high and low TOP-GFP cell fractions. 4 sampl...
ORGANISM(S): Homo sapiens 
2009-12-01 | E-GEOD-17375 | biostudies-arrayexpress
UnknownThe HDAC inhibitor SAHA regulates CBX2 stability via a SUMO-triggered ubiquitin-mediated pathway in leukemia.
Not available
S-EPMC5945585 | biostudies-literature
TranscriptomicsmiR-200 overexpression in colorectal cancer lines
Unsupervised classification of gene expression profiles has resulted in the identification of biologically and clinically distinct colon cancer subtypes (CCSs). The subtype that associates with poor clinical outcome displays a mesenchymal gene expression profile. No driver mutation has been identifi...
ORGANISM(S): Homo sapiens 
2015-09-01 | E-GEOD-65551 | biostudies-arrayexpress
TranscriptomicsGene expression in colon cancer stem cells (CSC) cultures identified by Wnt signaling levels
Primary colon CSC cultures were transduced with a Wnt responsive construct (TOP-GFP). 10% highest and lowest TOP-GFP cell fractions were FACS sorted and arrayed. Primary colon CSC cultures with a responsive construct (TOP-GFP): high and low TOP-GFP cell fractions. 12 samples.
ORGANISM(S): Homo sapiens 
2011-11-05 | E-GEOD-33112 | biostudies-arrayexpress
UnknownIntestinal Apc-inactivation induces HSP25 dependency
Not available
S-SCDT-10_15252-EMMM_202216194 | biostudies-other
TranscriptomicsAMC tubular and serrated adenomas
Profiling project of a panel of tubular adenoma and serrated adenoma patient material collected in the Academic Medical Center (AMC) in Amsterdam, The Netherlands. The aim of the study was to compare the expression profiles of different types of colon cancer precursor lesions (tubular versus serrate...
ORGANISM(S): Homo sapiens 
2013-04-14 | E-GEOD-45270 | biostudies-arrayexpress
ProteomicsIntegrated Multi-Omics Reveal Polycomb Repressive Complex 2 Restricts Human Trophoblast Induction
Human naive pluripotent stem cells have unrestricted lineage potential. Underpinning this property, naive cells are thought to lack chromatin-based lineage barriers. However, this assumption has not been tested. Here, we define the chromatin-associated proteome, histone post-translational modificati...
ORGANISM(S): Homo sapiens (Human) 
2022-05-09 | PXD032792 | Pride
H3k27me3 Trophoblast fate Polycomb repressive complex 2 (prc2) Chromatin proteomes Human pluripotent stem cells 
UnknownDaratumumab plus lenalidomide/bortezomib/dexamethasone in Black patients with transplant-eligible newly diagnosed multiple myeloma in GRIFFIN.
Not available
S-EPMC9007985 | biostudies-literature
UnknownHigh-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations.
Not available
S-EPMC7002524 | biostudies-literature
TranscriptomicsAMC colon cancer AJCCII
Profiling project of CRC patient material collected in the Academic Medical Center (AMC) in Amsterdam, The Netherlands. We focused on a set of 90 AJCC stage II patients that underwent intentionally curative surgery in the years 1997-2006 (AMC-AJCCII-90). Extensive medical records are kept from these...
ORGANISM(S): Homo sapiens 
2011-11-05 | E-GEOD-33113 | biostudies-arrayexpress
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