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ProteomicsNovel genetic mutations in pyrimidine salvage pathway enzymes from Cryptococcus neoformans contribute to reduced susceptibility against 5-fluorocytosine
The most common cause of cryptococcal meningitis is Cryptococcus neoformans. The addition of 5-fluorocytosine to the treatment of patient with this potentially fatal infection significantly improves disease outcome. However, developing resistance to this drug is a serious problem in patient manageme...
ORGANISM(S): Cryptococcus neoformans var. grubii Cryptococcus neoformans var. neoformans 
2024-07-29 | PXD044249 | Pride
Pyrimidine salvage pathway Proteomics Cryptococcus neoformans Resistance 5-fluorocytosine 
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