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TranscriptomicsTCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions
Surprisingly few pathways signal between cells, raising questions about mechanisms for tissue-specific responses. In particular, Wnt ligands signal in many mammalian tissues, including the intestinal epithelium, where constitutive signaling causes cancer. Genome-wide analysis of DNA cis-regulatory r...
ORGANISM(S): Homo sapiens 
2010-08-11 | E-GEOD-22572 | biostudies-arrayexpress
TranscriptomicsThe transcription factor CDX2 maintains active enhancer in intestinal villus cells in vivo
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-02-05 | E-GEOD-34568 | biostudies-arrayexpress
GenomicsHistone methylation and transcription factor binding during intestinal cell differentation
Cell differentiation requires epigenetic modulation of tissue-specific genes and activities of master transcriptional regulators, which are recognized for their dominant control over cellular programs. Using novel epigenomic methods, we characterized enhancer elements specifically modified in differ...
ORGANISM(S): Mus musculus 
2010-11-17 | E-GEOD-23436 | biostudies-arrayexpress
TranscriptomicsFAIRE-chip in MCF7 and LNCaP
The compaction degree of chromatin is intimately related to its functionality and active cis-regulatory elements typically exist within open chromatin regions depleted in nucleosomes (Heintzman et al. 2007; Boyle et al. 2008). These domains can be identified using Formaldehyde-Assisted Isolation of ...
ORGANISM(S): Homo sapiens 
2010-05-14 | E-GEOD-11579 | biostudies-arrayexpress
UnknownFILIP1L Loss Is a Driver of Aggressive Mucinous Colorectal Adenocarcinoma and Mediates Cytokinesis Defects through PFDN1.
Not available
S-EPMC8563430 | biostudies-literature
UnknownTCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions.
Not available
S-EPMC2930576 | biostudies-literature
UnknownDynamic Reprogramming of Stromal Pdgfra-expressing cells during WNT-Mediated Transformation of the Intestinal Epithelium.
Not available
S-EPMC11785226 | biostudies-literature
UnknownThe 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer.
Not available
S-EPMC2763485 | biostudies-literature
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