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TranscriptomicsDifferential Gene Expression Profile in the Rat Caudal Vestibular Nucleus is Associated with Individual Differences in Motion Sickness Susceptibility
Motion sickness susceptible (MSS) and insusceptible (inMSS) rats were identified by quantifying rotation-induced MS symptoms: defecation and spontaneous locomotion activity. Microarray analysis was used to screen differentially expressed genes in the caudal vestibular nucleus (CVN) af...
ORGANISM(S): Rattus norvegicus 
2015-01-08 | E-MTAB-3213 | biostudies-arrayexpress
TranscriptomicsMicroarray Analysis in Vestibular Schwannomas
Vestibular Schwannomas are benign neoplasms that arise from the vestibular nerve. The hallmark of these tumors is the biallelic inactivation of NF2. Transcriptomic alterations, such as the Nrg1/ErbB2 pathway, have been described in Schwannomas. Here, we have performed a whole transcriptomic analysis...
ORGANISM(S): Homo sapiens 
2013-03-01 | E-GEOD-39645 | biostudies-arrayexpress
TranscriptomicsGene profiles during vestibular compensation in unilateral labyrinthectomized rats
Microarray analysis was used to examine the expression of genes upregulated or downregulated in the ipsilateral vestibular nucleus at 1 and 7 days following unilateral labyrinthectomy. Changes in gene expression during the chronic phase of vestibular compensation following unilateral labyrinthectomy...
ORGANISM(S): Rattus norvegicus 
2011-11-16 | E-GEOD-32437 | biostudies-arrayexpress
TranscriptomicsIdentification of microRNA targets in the mammalian inner ear using a comprehensive transcriptome and proteome integrated approach
We have employed a novel approach for the identification of functionally important microRNA (miRNA)-target interactions using integrated miRNA, transcriptome and proteome profiles with advanced in silico analysis. By looking at both the transcript and protein levels of expression, a thorough coverag...
ORGANISM(S): Mus musculus 
2011-04-20 | E-GEOD-23081 | biostudies-arrayexpress
TranscriptomicsGlobal Profiling in Vestibular Schwannomas Shows Critical Deregulation of MicroRNAs and Upregulation in those included in Chromosomal Region 14q32
Background: Vestibular Schwannomas are benign tumors that arise from Schwann cells in the VIII cranial pair and usually present NF2 gene mutations and/or loss of heterozygosity on chromosome 22q. Deregulation has also been found in several genes, such as ERBB2 and NRG1. MicroRNAs are non-coding RNAs...
ORGANISM(S): Homo sapiens 
2014-03-24 | E-GEOD-43571 | biostudies-arrayexpress
TranscriptomicsMJAY analysis of vestibular macula RNA obtained from Bronx waltzer and control mice.
The spontaneous mutant Bronx waltzer (bv) mouse line is characterized by deafness and balance defect. We located the bv mutation to the Srrm4 gene which encodes a regulator of alternative pre-mRNA splicing. We found that Srrm4 is expressed in balance and hearing organs (i.e. in the vestibular macula...
ORGANISM(S): Mus musculus 
2012-10-21 | E-GEOD-33590 | biostudies-arrayexpress
GenomicsIdentification of cell types in medial vestibular nucleus and their response to unilateral vestibular loss
Identification of cell types in medial vestibular nucleus and their response to unilateral vestibular loss
PRJNA601339 | ENA
UnknownFrom vestibular implant to cortex: electrically evoked vestibular responses.
Not available
S-EPMC12122595 | biostudies-literature
TranscriptomicsGene expression study of developing mammalian vestibular organ of wild type and Insulin-Like Growth Factor I deficient mice using Affymetrix whole transcript arrays
Insulin like growth factor 1 (IGF-1) has a central role in mammalian hearing and hearing loss. The auditory and vestibular systems form the inner ear and have a common developmental origin. During chicken early development IGF-1 modulates neurogenesis of the cochleovestibular ganglion but no further...
ORGANISM(S): Mus musculus 
2015-01-23 | E-GEOD-65202 | biostudies-arrayexpress
UnknownVestibular loss disrupts visual reactivity in the alpha EEG rhythm.
Not available
S-EPMC10368920 | biostudies-literature
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