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GenomicsGene expression analysis in the Brainstem of Vglut2:Ndufs4cKO mice
Gene expression analysis in the Brainstem of Vglut2:Ndufs4cKO mice
PRJNA516446 | ENA
TranscriptomicsGene expression analysis in the Brainstem of Vglut2:Ndufs4cKO mice
Leigh Syndrome is characterized by symmetrical brain lesions and neuroinflammation in select nuclei, predominantly brainstem and/or basal ganglia. Accordingly, Ndufs4-deficient mice present overt lesions in brainstem, olfactory bulb, and basal ganglia. To define the contribution of Ndufs4 deficiency...
ORGANISM(S): Mus musculus 
2019-03-31 | GSE125470 | GEO
ProteomicsSynaptic vesicles that store monoamines and glutamate differ in protein composition
Neuromodulators such as monoamines assure essential brain functions but relatively little is known about their mechanism of release. While recent work has advanced our knowledge of active zone architecture in dopamine axons, release machinery within the synaptic vesicle (SV) remains poorly understoo...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-08 | PXD073685 | Pride
Synaptic vesicles Tmt Vmat2 Dopamine release Vglut2 
GenomicsCPEB2-activated axonal translation of VGLUT2 mRNA promotes glutamatergic transmission and presynaptic plasticity
CPEB2-activated axonal translation of VGLUT2 mRNA promotes glutamatergic transmission and presynaptic plasticity
PRJNA860927 | ENA
GenomicsGene expression profiling of Vglut2 neurons in the vestibular nucleus (VN)
Gene expression profiling of Vglut2 neurons in the vestibular nucleus (VN)
PRJNA705178 | ENA
ProteomicsAnalysis of posttranslational modifications in the Vesicular Glutamate Transporter 2 (Slc17a6)
In contrast to most secondary active transporters, glutamate uptake into synaptic vesicles is not coupled to an ion but driven instead by membrane potential and regulated allosterically by protons and chloride. To understand the mechanisms, we determined high-resolution criyo-EM structures of VGLUT2...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-04-16 | PXD061514 | Pride
Palmitoyl cysteine Rat Vglut2 
UnknownRegulating nociceptive transmission by VGluT2-expressing spinal dorsal horn neurons.
Not available
S-EPMC6263733 | biostudies-literature
UnknownRole for VGLUT2 in selective vulnerability of midbrain dopamine neurons.
Not available
S-EPMC5785252 | biostudies-literature
OtherCPEB2-activated axonal translation of VGLUT2 mRNA promotes glutamatergic transmission and presynaptic plasticity
Background Local translation at synapses is important for rapidly remodeling the synaptic proteome to sustain long-term plasticity and memory. While the regulatory mechanisms underlying memory-associated local translation have been widely elucidated in the postsynaptic/dendritic region, there is no ...
ORGANISM(S): Mus musculus 
2024-07-08 | GSE208738 | GEO
UnknownVGLUT2 Functions as a Differential Marker for Hippocampal Output Neurons.
Not available
S-EPMC6176088 | biostudies-literature
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