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ProteomicsIdentification of Vha68-3 binding proteins by LC-MS/MS
To explore the regulatory network involving Vha68-3 binding proteins, immunocoprecipitation (IP) experiments were performed in S2 cells via LC-MS/MS analysis and Label-free quantification.
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2025-05-26 | PXD060509 | Pride
Vha68-3  drosophila schneider 2  immunocoprecipitation  lc-ms/ms 
TranscriptomicsHeLa cells treated with V-ATPase inhibitors or with desoxyferramine compared to HeLa in DMSO or medium with low LDL
Expression data from HeLa cells treated with V-ATPase inhibitors or with desoxyferramine compared to HeLa treated with DMSO or medium with low LDL To determine which genes respond first to low concentrations of V-ATPase inhibition, we treated HeLa cells with two different V-ATPase inhibitors, bafil...
ORGANISM(S): Homo sapiens 
2010-07-22 | E-GEOD-16870 | biostudies-arrayexpress
UnknownLgl reduces endosomal vesicle acidification and Notch signaling by promoting the interaction between Vap33 and the V-ATPase complex.
Not available
S-EPMC6437781 | biostudies-literature
TranscriptomicsRNA-seq of whole tissue of 3 days post fertilization atp6v1e1b-deficient zebrafish larvae and wild-type controls
Cutis laxa (CL) syndromes are a heterogenous group of connective tissue disorders that share a loose, redundant skin as a common clinical feature. The systemic features vary among the different subtypes. CL is caused by mutations in genes encoding for components of the extracellular matrix (FBLN4, F...
ORGANISM(S): Danio rerio 
2021-01-29 | E-MTAB-8824 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidospsis etiolated seedlings Col-0 wild type compared to det3 mutants under various growth conditions
Arabidopsis etiolated seedlings (4d old) Col-0 wild type compared to det3 mutants under various growth conditions
ORGANISM(S): Arabidopsis thaliana 
2008-10-09 | E-MEXP-1468 | biostudies-arrayexpress
ProteomicsTan_V-ATPase_mEAK-7_interaction_2022
This dataset consists of 4 raw MS files and associated peak lists and result files, acquired on a TripleTOF 6600 mass spectrometer operated in Data Dependent Acquisition mode. Samples were analyzed by Geoffrey Hesketh. The files are associated with a manuscript in Life Science Alliance by Tan et al...
ORGANISM(S): Sus Scrofa (ncbitaxon:9823) Rattus (ncbitaxon:10114) 
2022-06-28 | MSV000089750 | MassIVE
TranscriptomicsDistinct signal transduction pathways downstream of the (P)RR revealed by microarray and ChIP-chip analyses [Expt: ChIP-chip]
We performed a set of microarray and chromatin-immunoprecipitation (ChIP)-chip experiments using siRNA against the (pro)renin receptor ((P)RR), stable overexpression of PLZF, the PLZF translocation inhibitor genistein and the specific V-ATPase inhibitor bafilomycin to dissect transcriptional pathway...
ORGANISM(S): Homo sapiens 
2013-07-05 | E-GEOD-39960 | biostudies-arrayexpress
TranscriptomicsDistinct signal transduction pathways downstream of the (P)RR revealed by microarray and ChIP-chip analyses [Expt: PLZF_HEK]
Within the overall project, we performed a set of microarray and chromatin-immunoprecipitation (ChIP)-chip experiments using siRNA against the (pro)renin receptor ((P)RR), stable overexpression of PLZF, the PLZF translocation inhibitor genistein and the specific V-ATPase inhibitor bafilomycin to dis...
ORGANISM(S): Homo sapiens 
2013-07-05 | E-GEOD-39961 | biostudies-arrayexpress
TranscriptomicsDistinct signal transduction pathways downstream of the (P)RR revealed by microarray and ChIP-chip analyses [Expt: Geni_Bafi]
Within the overall project, we performed a set of microarray and chromatin-immunoprecipitation (ChIP)-chip experiments using siRNA against the (pro)renin receptor ((P)RR), stable overexpression of PLZF, the PLZF translocation inhibitor genistein and the specific V-ATPase inhibitor bafilomycin to dis...
ORGANISM(S): Homo sapiens 
2013-07-05 | E-GEOD-39962 | biostudies-arrayexpress
TranscriptomicsConditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration
ATP6AP2 is an essential accessory component of the vacuolar H+ ATPase (V-ATPase) and has been associated with intellectual disabilities (ID) and Parkinsonism. ATP6AP2 has been implicated in several signaling pathways, but little is known about its role in the nervous system. To decipher its function...
ORGANISM(S): Mus musculus 
2015-09-22 | E-GEOD-67541 | biostudies-arrayexpress
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