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ProteomicsThe Yin and Yang of GDF15: a secreted biomarker of eribulin response in breast cancer cells, yet required for survival of drug tolerant persister (DTP) cells
Drug tolerant persister (DTP) cells enter into a reversible slow-cycling state after cancer drug treatment. These cells are the living proof of response to a drug, and an interesting experimental subject for biomarker discovery. Here, we performed proteomic characterization of the breast cancer (BC)...
ORGANISM(S): Homo sapiens (Human) 
2023-01-09 | PXD034037 | Pride
Eribulin Drug tolerance Growth differentiation factor (gdf15) Secretome. Drug tolerant persister (dtp) Breast cancer (bc) 
ProteomicsCirculating SOD2 is a Response Biomarker for Neoadjuvant Therapy in Breast Cancer
There is a great need of non-invasive tools that inform of an early molecular response to cancer therapeutic treatment. Here, we have tested the hypothesis that proteolytically resistant proteins could be candidate circulating tumor biomarkers for cancer therapy. Proteins resistant to proteolysis ar...
ORGANISM(S): Homo sapiens (Human) 
2023-01-09 | PXD032359 | Pride
Proteolysis-resistant proteins Sod2 Biomarker 
UnknownEpigenetic loss of the transfer RNA-modifying enzyme TYW2 induces ribosome frameshifts in colon cancer.
Not available
S-EPMC7456070 | biostudies-literature
TranscriptomicsGene-expression profiles of formalin-fixed, paraffin-embedded human intrahepatic cholangiocarcinoma
BACKGROUND & AIMS: Cholangiocarcinoma, the second most common liver cancer, can be classified as intrahepatic (ICC) or extrahepatic. We performed an integrative genomic analysis of ICC samples from a large series of patients. METHODS: We performed gene expression profile, high-density single nucleot...
ORGANISM(S): Homo sapiens 
2013-01-24 | E-GEOD-32225 | biostudies-arrayexpress
TranscriptomicsDNA copy number profiles of formalin-fixed, paraffin-embedded human intrahepatic cholangiocarcinoma
BACKGROUND & AIMS: Cholangiocarcinoma, the second most common liver cancer, can be classified as intrahepatic (ICC) or extrahepatic. We performed an integrative genomic analysis of ICC samples from a large series of patients. METHODS: We performed gene expression profile, high-density single nucleot...
ORGANISM(S): Homo sapiens 
2013-01-24 | E-GEOD-33326 | biostudies-arrayexpress
UnknownPRL-3 is essentially overexpressed in primary colorectal tumours and associates with tumour aggressiveness.
Not available
S-EPMC2584959 | biostudies-literature
UnknownChromatin activity of IκBα mediates the exit from naive pluripotency.
Not available
S-EPMC12543326 | biostudies-literature
UnknownNon-Lynch Familial and Early-Onset Colorectal Cancer Explained by Accumulation of Low-Risk Genetic Variants.
Not available
S-EPMC8345397 | biostudies-literature
UnknownPVR (CD155) epigenetic status mediates immunotherapy response in multiple myeloma.
Not available
S-EPMC11588647 | biostudies-literature
UnknownGene Amplification-Associated Overexpression of the Selenoprotein tRNA Enzyme TRIT1 Confers Sensitivity to Arsenic Trioxide in Small-Cell Lung Cancer.
Not available
S-EPMC8070726 | biostudies-literature
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