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MetabolomicsSerine and 1-carbon metabolism are required for HIF-mediated protection against retinopathy of prematurity
We determined which metabolic pathways are activated by hypoxia-inducible factor 1-mediated (HIF-1-mediated) protection against oxygen-induced retinopathy (OIR) in newborn mice, the experimental correlate to retinopathy of prematurity, a leading cause of infant blindness. HIF-1 coordinates the chang...
2019-07-05 | MTBLS856 | MetaboLights
UnknownQuantum computational advantage with a programmable photonic processor.
Not available
S-EPMC9159949 | biostudies-literature
Transcriptomicsshort-term effect of N and S supply shifts on gene expression in wheat grain
Nitrogen and Sulfur supply play an important role in modulating wheat grain development. We studied the short-term effect of shifting N and S supply levels at mid-way through grain filling on gene expression by microarray analysis. Please note: Factor Value[sampling time]: indicates when the samples...
ORGANISM(S): Triticum aestivum 
2015-06-01 | E-MTAB-1920 | biostudies-arrayexpress
UnknownDecreased but diverse activity of cortical and thalamic neurons in consciousness-impairing rodent absence seizures.
Not available
S-EPMC9832004 | biostudies-literature
TranscriptomicsN and S regulation of wheat storage protein accumulation
Seed storage proteins (SSP) play a central role in providing carbon (C), nitrogen (N), and sulfur (S) resources during seed germination. Their content and composition are essential determinants shaping wheat end-use value. Molecular mechanisms underlying the developmental and nutritional regulation ...
ORGANISM(S): Triticum aestivum 
2015-06-15 | E-MTAB-1782 | biostudies-arrayexpress
MetabolomicsVeterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs (T. brucei assay)

Livestock diseases caused by Trypanosoma congolense, T. vivax and T. brucei, collectively known as nagana, are responsible for billions of dollars in lost food production annually. There is an urgent need for novel therapeutics. Encouragingly, promising antitrypanosomal benzoxaboroles are under v...

2020-09-23 | MTBLS1474 | MetaboLights
MetabolomicsVeterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs (T. congolense assay)

Livestock diseases caused by Trypanosoma congolense, T. vivax and T. brucei, collectively known as nagana, are responsible for billions of dollars in lost food production annually. There is an urgent need for novel therapeutics. Encouragingly, promising antitrypanosomal benzoxaboroles are under v...

2020-10-22 | MTBLS1309 | MetaboLights
ProteomicsProteogenomics reanalysis of human testis data
Reanalysis of the human testis tissue dataset acquired for the Chromosome-centric Human Proteome Project (C-HPP; PRIDE project PXD002179), with a focus on identifying novel peptides for genome annotation.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-13 | MSV000083973 | MassIVE
ModelsHeitzler2012 - GPCR signalling
This model is from the article: Competing G protein-coupled receptor kinases balance G protein and β-arrestin signaling Heitzler D, Durand G, Gallay N, Rizk A, Ahn S, Kim J, Violin JD, Dupuy L, Gauthier C, Piketty V, Crépieux P, Poupon A, Clément F, Fages F, Lefkowit...
2024-09-02 | BIOMD0000000842 | BioModels
TranscriptomicsGene expression profiles of CD4+CD25+ Tregs from NOD and B6.H2g7 mice
The NOD (nonobese diabetic) mouse strain develops a characteristic autoimmune syndrome that closely resembles human type I diabetes. It has been suggested that NOD mice exhibit both numerical deficiency in CD4+CD25+ regulatory T cells (Treg) and reduced suppressive activity. We compared sorted CD4...
ORGANISM(S): Mus musculus 
2008-12-19 | E-GEOD-6813 | biostudies-arrayexpress
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