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ProteomicsViral lncRNA upregulates multiple A+U-richViral lncRNA upregulates multiple A+U-rich transcripts to promote cell motility and viral dissemination transcripts to promote cell motility and viral dissemination
Long non-coding RNAs are frequently associated with broad modulation of gene expression and thus provide the cell with the ability to synchronize entire metabolic processes. We used transcriptomic and proteomic approaches to investigate whether the most abundant human cytomegalovirus-encoded lncRNA,...
ORGANISM(S): Human herpesvirus 5 strain Merlin Homo sapiens (Human) 
2021-07-27 | PXD022277 | Pride
Cell motility Gene regulation Lncrna A+u rich Transcriptomics Human cytomegalovirus Viral dissemination 
ProteomicsThe global Proteome and Ubiquitinome of bacterial and viral co-infected Bronchial Epithelial Cells
Viral infections facilitate bacterial trafficking to the lower respiratory tract resulting in bacterial viral co infections. Bacterial dissemination to the lower respiratory tract is enhanced by influenza A virus induced epithelial cell damage and dysregulation of immune responses. Epithelial cells ...
ORGANISM(S): Homo Sapiens Staphylococcus Aureus Influenza A Virus (a/germany-by/74/2009(h1n1)) Streptococcus Pyogenes 
2022-06-13 | PXD026625 | panorama
GenomicsMARCO+ lymphatic endothelial cells sequester arthritogenic alphaviruses in the draining lymph node and limit viral dissemination
MARCO+ lymphatic endothelial cells sequester arthritogenic alphaviruses in the draining lymph node and limit viral dissemination
PRJNA730926 | ENA
UnknownMARCO+ lymphatic endothelial cells sequester arthritogenic alphaviruses to limit viremia and viral dissemination.
Not available
S-EPMC8591538 | biostudies-literature
MetabolomicsNMR-based metabolic profiling provides diagnostic and prognostic information in critically ill children with suspected infection

Sepsis, defined as life-threatening organ dysfunction caused by infection is difficult to distinguish clinically from infection or post-operative inflammation. We hypothesized that in a heterogeneous group of critically ill children, there would be different metabolic profiles between post-operat...

2020-11-19 | MTBLS563 | MetaboLights
UnknownDefective viral genomes from chikungunya virus are broad-spectrum antivirals and prevent virus dissemination in mosquitoes.
Not available
S-EPMC7870000 | biostudies-literature
UnknownZika virus enhances monocyte adhesion and transmigration favoring viral dissemination to neural cells.
Not available
S-EPMC6764950 | biostudies-literature
TranscriptomicsECM-dependent gene expression in normal and tumor-derived mammary organoids
A critical step in metastasis is cancer cell dissemination. Dissemination and metastasis are associated with specific genetic changes and changes in extracellular matrix (ECM), but how these changes interact to enable dissemination remains unclear. Here we tested the importance of ECM to disseminat...
ORGANISM(S): Mus musculus 
2012-08-16 | E-GEOD-39173 | biostudies-arrayexpress
UnknownLymphatic Vessels Balance Viral Dissemination and Immune Activation following Cutaneous Viral Infection.
Not available
S-EPMC5621787 | biostudies-literature
Genomicsviral metagenome
Arbovirus minority variants required to traverse bottlenecks in the mosquito
PRJNA390970 | ENA
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