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ProteomicsMetaproteomics of viral concentrates at deep chlorophyll maximum of Scouth China Sea
Marine viral concentrates (VCs) contains a substantial amount of non-cellular biological particles, e.g. viruses, gene transfer agents (GTAs) and membrane vesicles that are ecological significant. Metagenomic sequencing of VCs has been extensively applied to study the diversity and function potentia...
ORGANISM(S): environmental samples <unclassified> 
2018-05-02 | PXD007174 | Pride
Virua 56 kda selenium-binding protein Viral concentrates Metaproteomics 
ProteomicsUnderstanding early AutoAb signatures in Pituitary Adenomas using CDI HuProt™ (Human Proteome Microarray)
CDI HuProt™ (Human Proteome Microarray), was used to study Pituitary Adenomas PAs (Acromegaly, Cushing's and NFPA) using serum samples, from around 14 individuals (4 Healthy control, 4 Acromegaly, 3 Cushing’s and 3 NFPAs patient samples) were used study their autoantibody profiles. Patient serum sam...
ORGANISM(S): Homo sapiens 
2022-09-30 | E-MTAB-11947 | biostudies-arrayexpress
ProteomicsProfiling proteome-scale antibody responses to M. tuberculosis
This SuperSeries is composed of the following subset Series: GSE30721: Profiling proteome-scale antibody responses to M. tuberculosis proteins in sera of macaques infected with M. tuberculosis GSE30722: Profiling proteome-scale antibody responses to M. tuberculosis proteins in TB suspect's sera Refe...
ORGANISM(S): Homo sapiens 
2012-07-05 | E-GEOD-31368 | biostudies-arrayexpress
ProteomicsTARA Oceans Viral Proteins - Illuminating structural proteins in viral "dark matter" with metaproteomics
A grand challenge in biology is the lack of annotation for much of global sequence space. In particular, while microbes and their viruses are critical to Earth System functioning, surveys of their communities in nature routinely return genes of unknown function, particularly for viruses. This hamper...
ORGANISM(S): environmental samples 
2016-02-25 | PXD000938 | Pride
Viral proteomics Virus Tara Viral Proteomics Proteins 
ProteomicsThe global Proteome and Ubiquitinome of bacterial and viral co-infected Bronchial Epithelial Cells
Viral infections facilitate bacterial trafficking to the lower respiratory tract resulting in bacterial viral co infections. Bacterial dissemination to the lower respiratory tract is enhanced by influenza A virus induced epithelial cell damage and dysregulation of immune responses. Epithelial cells ...
ORGANISM(S): Homo Sapiens Staphylococcus Aureus Influenza A Virus (a/germany-by/74/2009(h1n1)) Streptococcus Pyogenes 
2022-06-13 | PXD026625 | panorama
UnknownDeep mutation, insertion and deletion scanning across the Enterovirus A proteome reveals constraints shaping viral evolution.
Not available
S-EPMC11726453 | biostudies-literature
ProteomicsProfiling antibody responses to M. tuberculosis proteins in TB suspects’ sera using full-proteome microarrays.
Understanding the immune response to tuberculosis requires greater knowledge of humoral responses. To characterize antibody targets and the effect of disease parameters on target recognition, we developed a systems immunology approach that integrated detection of antibodies against the entire Mycob...
ORGANISM(S): Homo sapiens 
2010-07-13 | E-GEOD-19433 | biostudies-arrayexpress
ProteomicsAdenovirus remodeling of the host proteome and of host factors associating with viral genomes
Viral infections are associated with extensive remodeling of the cellular proteome. Viruses encode gene products that manipulate host proteins to redirect cellular processes or subvert antiviral immune responses. One way in which host antiviral proteins antagonize viral infection is by associating w...
ORGANISM(S): Viruses Homo sapiens (Human) 
2021-08-11 | PXD025339 | Pride
Intrinsic defense Dna virus Ipond Virus infection Adenovirus 
ProteomicsProfiling proteome-scale antibody responses to M. tuberculosis proteins in TB suspect's sera
Human infection with Mycobacterium tuberculosis results in a continuum of ill-defined, clinical manifestations with stable latent M. tuberculosis infection (LTBI) and severe active disease at the ends. Identifying different states of infection is of importance to tuberculosis (TB) control since ris...
ORGANISM(S): Homo sapiens 
2012-07-05 | E-GEOD-30722 | biostudies-arrayexpress
ProteomicsProfiling proteome-scale antibody responses to M. tuberculosis proteins in sera of macaques infected with M. tuberculosis
Human infection with Mycobacterium tuberculosis results in a continuum of ill-defined, clinical manifestations with stable latent M. tuberculosis infection (LTBI) and severe active disease at the ends. Identifying different states of infection is of importance to tuberculosis (TB) control since ris...
ORGANISM(S): Macaca fascicularis 
2012-07-05 | E-GEOD-30721 | biostudies-arrayexpress
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