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TranscriptomicsA mutation of RNA polymerase β’ subunit (RpoC) converts heterogeneously vancomycin-intermediate S. aureus (hVISA) into ‘slow-VISA’ (sVISA)
Various mutations in the rpoB gene, which encodes the RNA polymerase beta subunit, are associated with increased vancomycin (VAN) resistance in vancomycin-intermediate S. aureus (VISA) and hetero-VISA (hVISA) strains. We reported that rpoB mutations are also linked to the expression of the recently ...
ORGANISM(S): Staphylococcus aureus 
2015-05-08 | E-GEOD-65338 | biostudies-arrayexpress
ProteomicsProtein Biomarker Discovery for Methicillin-sensitive, Heterogeneous Vancomycin-Intermediate, and Vancomycin-intermediate Staphylococcus aureus Strains using Label-Free Data-Independent Acquisition Proteomics
90 S. aureus isolates were analyzed for protein biomarker discovery, including MSSA, vancomycin-susceptible S. aureus (VSSA), hVISA, and VISA strains. Label-free data-independent acquisition proteomics was used to identify protein biomarkers that allow for discrimination among MSSA, hVISA, and VISA ...
ORGANISM(S): Staphylococcus Aureus (ncbitaxon:1280) 
2020-07-18 | MSV000085776 | MassIVE
TranscriptomicsA Single Amino-Acid Substitution of RNA Polymerase ß subunit Confers A Novel Class of VISA phenotype on hVISA Strain Mu3
hVISA clinical strain Mu3 spontaneously generates VISA at an extremely high frequency (1x10-6 or greater) within its cell population. The VISA-converted mutant strains generally grow slower than their parent hVISA strain, but they usually form colonies on vancomycin-containing agar plates after 48 h...
ORGANISM(S): Staphylococcus aureus 
2014-03-31 | GSE50826 | GEO
TranscriptomicsA Single Amino-Acid Substitution of RNA Polymerase M-CM-^_ subunit Confers A Novel Class of VISA phenotype on hVISA Strain Mu3
hVISA clinical strain Mu3 spontaneously generates VISA at an extremely high frequency (1x10-6 or greater) within its cell population. The VISA-converted mutant strains generally grow slower than their parent hVISA strain, but they usually form colonies on vancomycin-containing agar plates after 48 h...
ORGANISM(S): Staphylococcus aureus 
2014-03-31 | E-GEOD-50826 | biostudies-arrayexpress
TranscriptomicsA mutation of RNA polymerase β’ subunit (RpoC) converts heterogeneously vancomycin-intermediate S. aureus (hVISA) into ‘slow-VISA’ (sVISA)
Various mutations in the rpoB gene, which encodes the RNA polymerase beta subunit, are associated with increased vancomycin (VAN) resistance in vancomycin-intermediate S. aureus (VISA) and hetero-VISA (hVISA) strains. We reported that rpoB mutations are also linked to the expression of the recently ...
ORGANISM(S): Staphylococcus aureus 
2015-05-08 | GSE65338 | GEO
UnknownVISA is required for B cell expression of TLR7.
Not available
S-EPMC3244560 | biostudies-literature
UnknownComprehensive identification of mutations responsible for heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA)-to-VISA conversion in laboratory-generated VISA strains derived from hVISA clinical strain Mu3.
Not available
S-EPMC3837870 | biostudies-literature
UnknownPhysalin F Promotes AFG3L2-Mediated Degradation of VISA/MAVS to Suppress Innate Immune Response to RNA Virus.
Not available
S-EPMC12844614 | biostudies-literature
UnknownSmall self-RNA generated by RNase L amplifies antiviral innate immunity.
Not available
S-EPMC3638316 | biostudies-literature
UnknownA mutation of RNA polymerase β' subunit (RpoC) converts heterogeneously vancomycin-intermediate Staphylococcus aureus (hVISA) into "slow VISA".
Not available
S-EPMC4468653 | biostudies-literature
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