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TranscriptomicsTranscription profiling by array of Streptococcus agalactiae strain 2603 V/R and isogenic Delta_csrRS mutant grown in the presence or in the absence of glucose
Comparative global gene expression analysis of the 2603 V/R Streptococcus agalactiae (Group B streptococcus, GBS) strain grown in a medium devoid of sugars versus bacteria incubated for 30 min in 55 mM glucose medium. To investigate whether glucose-dependent regulation of gene expression was modulat...
ORGANISM(S): Streptococcus agalactiae 
2013-07-15 | E-MTAB-1100 | biostudies-arrayexpress
ProteomicsCisplatin induces the rearrangement of RBPs on CDKN1B/p27 mRNA
Cisplatin (CP) is a chemotherapeutic drug that is used to cure different types of cancer. CP induces DNA damage and leads to cell cycle arrest. The cyclin-dependent kinase inhibitor 1B (CDKN1B), also termed p27, plays an important role in the drug response ; and increased levels of p27 correlated wi...
ORGANISM(S): Homo sapiens (Human) 
2019-09-27 | PXD008498 | Pride
Tobramaycin Rna aptamer Rbps Cdkn1b/p27 
ProteomicsProteomic Investigation of EVLP Tissue Lung Lobes
The aim of this work concerns the development of a proteomics workflow based on LC-MS/MS useful for a comprehensive study of molecular mechanisms related to the effect on the lung subjected to EVLP
ORGANISM(S): Rattus norvegicus (Rat) 
2018-11-28 | PXD006692 | Pride
Lung Evlp Proteomics 
TranscriptomicsA protective strategy against hyperinflammatory responses requiring the non-transcriptional actions of GPS2
The association between hyper-inflammatory states and numerous diseases is widely recognized, but our understanding of the molecular strategies that have evolved to prevent uncontrolled activation of inflammatory responses remains incomplete. Here, we report a critical, non-transcriptional role of G...
ORGANISM(S): Homo sapiens 
2012-03-23 | E-GEOD-35197 | biostudies-arrayexpress
TranscriptomicsHuman liver stem cells-derived microvesicles accelerate hepatic regeneration in partially hepatectomized rats
Several studies indicate that adult stem cells may improve the recovery from acute tissue injury. It has been suggested that they may contribute to tissue regeneration by the release of paracrine factors promoting proliferation of tissue resident cells. However, the factors involved remain unknown. ...
ORGANISM(S): Homo sapiens 
2010-05-08 | E-GEOD-15569 | biostudies-arrayexpress
TranscriptomicsTranscriptome and translatome profiling of CPX 90m effects in neuroblastoma cells CHP134
Neuroblastoma (NB) is the most frequent extracranial solid tumour of childhood. Clinical courses are highly variable, ranging from spontaneous regression/maturation to rapid progression despite intensive multimodal therapy. The estimation of 5-year event free survival in high-risk patients of only a...
ORGANISM(S): Homo sapiens 
2015-02-04 | E-GEOD-60675 | biostudies-arrayexpress
TranscriptomicsTh2 differentiation in a time course experiment and at single generation resolution
Mouse splenic naïve T cells were activated (with anti-CD3/CD28)and polarized towards the Th2 subtype with IL4 . Cells were collected at different time points during the differentiation and, at day 3 .5,were collected according to number of cell divisions and expression or absence of a specific diff...
ORGANISM(S): Mus musculus 
2016-04-01 | E-MTAB-3543 | biostudies-arrayexpress
UnknownDual role of EZH2 in megakaryocyte differentiation.
Not available
S-EPMC8554649 | biostudies-literature
TranscriptomicsRNA-seq of isolated human foetal and hiPSC L/M-opsin cone photoreceptor populations labelled using the AAV2/9.pR2.1.GFP reporter
The loss of cone photoreceptor cells, which are critical for optimal daylight vision, have the great impact on vision during retinal degenerations. Retinal differentiation of human induced pluripotent stem cell (hiPSC) sources could provide a renewable source of cone photoreceptors towards developin...
ORGANISM(S): Homo sapiens 
2018-04-20 | E-MTAB-6057 | biostudies-arrayexpress
TranscriptomicsDual role of EZH2 on megakaryocyte differentiation, analysis at different stages of maturation at day 9 of culture
EZH2, the enzymatic component of PRC2, has been identified as a key factor in hematopoiesis. EZH2 loss of function mutations have been found in myeloproliferative neoplasms, more particularly in myelofibrosis, but the precise function of EZH2 in megakaryopoiesis is not fully delineated. Here, we sho...
ORGANISM(S): Homo sapiens 
2021-11-02 | E-MTAB-8610 | biostudies-arrayexpress
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