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TranscriptomicsGene expression profile of mouse breast cancer V720 cells treated with vehicle or PD 0332991
D-cyclins represent components of cell cycle machinery. To test the efficacy of targeting D-cyclins in cancer treatment, we engineered mouse strains which allow acute and global ablation of individual D-cyclins in a living animal. Ubiquitous shutdown of cyclin D1 or inhibition of cyclin D associated...
ORGANISM(S): Mus musculus 
2012-10-16 | E-GEOD-40513 | biostudies-arrayexpress
TranscriptomicsGenotype-specific responses in intestinal lipid metabolism to complete dietary fish oil replacement by vegetable oil in Atlantic salmon
As part of a study investigating the effects of genotype on responses to sustainable feeds in Atlantic salmon, a microarray analysis of the intestine transcriptome of two family groups, identified as 'Lean' or 'Fat' (based on flesh lipid content), which were fed a diet containing either 100% fish oi...
ORGANISM(S): Salmo salar 
2012-03-01 | E-TABM-1173 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Atlantic salmon following dietary substitution of fish oil with vegetable oils
There is an increasing drive to replace fish oil (FO) in finfish aquaculture diets with vegetable oils (VO), driven by the short supply of FO derived from wild fish stocks. Little is known of the consequences for fish health after such substitution. The effect of dietary VO on hepatic gene expressio...
ORGANISM(S): Salmo salar 
2008-10-27 | E-TABM-478 | biostudies-arrayexpress
ProteomicsEarly NK-cell and T-cell dysfunction marks progression to severe dengue in patients with obesity and healthy weight
Dengue is a mosquito-borne virus infection affecting half of the world’s population for which therapies are lacking. The role of T and NK-cells in protection/immunopathogenesis remains unclear for dengue for dengue. We performed a longitudinal phenotypic, functional and transcriptional analyses of T...
ORGANISM(S): Homo sapiens (Human) 
2025-05-21 | PXD061694 | Pride
Dengue Cd4+ t-cells Cd8+ t-cells Co-inhibitory receptors Cytotoxic cells Severe dengue biomarkers Nk-cells Type-i ifn 
UnknownVO: The Vaccine Ontology.
Not available
S-EPMC12363946 | biostudies-literature
TranscriptomicsExposure time during postembryonic development influences persistent biological effects of the insecticide carbaryl in green frogs (Lithobates clamitans)
The impact of pesticides on amphibian metamorphosis may vary depending on developmental stage of individuals during the exposure period. Some anurans experience increased rates of development when exposure to the insecticide carbaryl occurs later in larval development. We exposed developing northern...
ORGANISM(S): Rana clamitans 
2013-02-21 | E-GEOD-42338 | biostudies-arrayexpress
UnknownMagnetic-field-induced insulator-metal transition in W-doped VO2 at 500 T.
Not available
S-EPMC7367819 | biostudies-literature
ProteomicsLC-MS/MS identification of Mycolactone protein targets
Mycolactone is a diffusible macrolide produced by the skin pathogen Mycobacterium ulcerans that suppresses the development of protective immunity against Buruli ulcer disease. In this proteomics study we aimed to identify proteins of which the expression levels changed upon mycolactone treatment. Ju...
ORGANISM(S): Homo sapiens (Human) 
2016-11-04 | PXD002971 | Pride
Mycolactone Silac Jurkat t-cells 
MetabolomicsThe impact of nutritional supplementation on sweat metabolomic content
Sweat is emerging as a prominent biosource for real-time human performance monitoring applications. Although promising, sources of variability must be identified to truly utilize sweat for biomarker applications. In this proof-of-concept study, a targeted metabolomics method was applied to sweat col...
2021-03-15 | MTBLS2427 | MetaboLights
UnknownTumor-Targeted Inhibition of Monocarboxylate Transporter 1 Improves T-Cell Immunotherapy of Solid Tumors.
Not available
S-EPMC7674253 | biostudies-literature
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