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ProteomicsComparative proteomics of paired human vocal fold and oral mucosa tissue
This dataset brief is about the descriptive proteomic comparison of human oral mucosa and vocal fold tissues by high-resolution mass spectrometry (CID-MS/MS). The vast majority of voice disorders is associated with changes of the unique but delicate tissue of the human vocal folds, wheras the abili...
ORGANISM(S): Homo sapiens (Human) 
2021-12-30 | PXD025519 | Pride
Oral mucosa Comparative proteomics Human tissue Vocal folds 
ProteomicsComparative Proteomics of PairedVocal Fold and Oral Mucosa Fibroblasts
Injuries of the vocal folds frequently heal with scar formation, which can have lifelong detrimental impact on voice quality. Current treatments to prevent or resolve scars of the vocal fold mucosa are highly unsatisfactory. In contrast, the adjacent oral mucosa is mostly resistant to scarring. Thes...
ORGANISM(S): Ovis aries 
2017-01-23 | PXD005106 | Pride
Lamina propria Oral mucosa Wound healing Fibrosis Laryngology Scar Vocal folds Fibroblasts 
ProteomicsProtein turnover during in vitro human vocal fold mucosa remodeling
We present here the first study evaluating the dynamic proteome changes in the remodeling process of decellularized tissue by reseeded cells using vocal fold mucosa as the model system.
ORGANISM(S): Homo sapiens (Human) 
2016-01-06 | PXD002734 | Pride
Silac Orbitrap Human Vocal fold mucosa 
GenomicsHuman induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure
Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure
PRJNA559267 | ENA
UnknownComparative proteomics of paired vocal fold and oral mucosa fibroblasts.
Not available
S-EPMC5389448 | biostudies-literature
TranscriptomicsHuman induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure
Development of treatments for vocal dysphonia has been inhibited by lack of human vocal fold (VF) mucosa models because of difficulty in procuring VF epithelial cells, epithelial cells’ limited proliferative capacity and absence of cell lines. We report development of engineered VF mucosae from hiPS...
ORGANISM(S): Homo sapiens 
2019-08-09 | GSE135548 | GEO
UnknownDescriptive proteomics of paired human vocal fold and buccal mucosa tissue.
Not available
S-EPMC9286793 | biostudies-literature
ProteomicsIntroducing a new type of organotypic laryngeal mucosa model
Research of human vocal fold (VF) biology is hampered by several factors. The sensitive microstructure of the VF mucosa is one of them and limits the in vivo research, as biopsies carry the unbearable risk of scarring. A laryngeal organotypic model consisting of VF epithelial cells and VF fibroblast...
ORGANISM(S): Homo sapiens (Human) 
2023-06-19 | PXD033688 | Pride
In vitro Proteomics Oral buccal mucosa Laryngeal mucosa model Vocal folds 
UnknownBioengineered vocal fold mucosa for voice restoration.
Not available
S-EPMC4669060 | biostudies-literature
UnknownDrainage of amniotic fluid delays vocal fold separation and induces load-related vocal fold mucosa remodeling.
Not available
S-EPMC7494656 | biostudies-literature
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