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We used quantitative mass spectrometry to analyze the effect of ML111 on the whole proteome of SK-N-MC cells. Results: ML111 treatment results in the accumulation of APC/C substrates suggesting that ML111 disrupts the cell cycle at or before the mitotic spindle assembly checkpoint.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-12-15 | MSV000086599 | MassIVE
Activation of the maternal immune system during pregnancy can fetal development, which can lead to postnatal susceptibility to a wide range of diseases, including cardiovascular, metabolic and psychiatric disorders. During maternal immune activation (MIA), the maternal body must balance its ressourc...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-13 | PXD039402 | Pride
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